Words similar to retinoblastoma
Example sentences for: retinoblastoma
How can you use “retinoblastoma” in a sentence? Here are some example sentences to help you improve your vocabulary:
A substantial percentage of human tumors lose the expression of the retinoblastoma tumor suppressor protein (Rb), important as a necessary condition for IFNg-mediated induction of MHCII [ 21 ] . Therefore, we wished to determine whether the poor IFNg inducibility of MHCII in LS1034, MSTO-211H and HepG2 cell lines could be explained by the loss of Rb.
Expression of the retinoblastoma protein is not lost in LS1034, MSTO-211H and HepG2 cell lines
It induces neuronal differentiation in retinoblastoma cells, protects retina neurons (including photoreceptors) from death by apoptosis and other insults, and has a morphogenetic effect on photoreceptor cells [ 3 4 5 6 ] . It also has neurotrophic effects on neurons from the cerebellum, hippocampus and spinal cord [ 7 8 9 10 11 12 ] . In the intact retina, this factor is identified as a secreted protein associated by ionic interactions with the interphotoreceptor matrix [ 13 14 ] , where GAGs are the major polyanionic components.
Candidate mechanisms for the block of proliferation by C/EBPα include 1) activation of the gene promoters of the cyclin-dependent kinase inhibitor p21 [ 37 ] , gadd45 [ 5 6 ] , gas2 and gas3 [ 38 39 ] , 2) post-transcriptional stabilization of p21 [ 22 ] , or 3) interactions of C/EBPα with cell cycle proteins including p21 [ 22 24 25 55 ] , CDK2 [ 25 36 ] , CDK4 [ 36 ] , retinoblastoma [ 54 ] , the retinoblastoma-related protein p107 [ 34 ] and the G1/S-regulating E2F transcription complex [ 26 33 ] (Fig.
Cell-associated HS proteoglycans can undergo regulated shedding from the membrane into the soluble extracellular matrix or culturing medium converting the membrane anchored molecules into soluble effectors [ 1 2 ] . In the conditioned media of all the tested batches of retinoblastoma cells, we detected heparin and HS with binding affinity for PEDF.
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