Words similar to replicons
Example sentences for: replicons
How can you use “replicons” in a sentence? Here are some example sentences to help you improve your vocabulary:
Ideally, to serve as dual vaccines against dengue as well as against other pathogens, the replicons should express the dengue NS1 protein [ 29 30 31 32 ] . So far, attempts to visualize NS1 production by Western blots have failed, presumably because of the low transfection efficiencies.
Although we have formally demonstrated expression, not replication, our previous demonstration of the replication [ 12 ] of dengue replicons lacking heterologous material suggests that the replicons described here, which contain heterologous material, are indeed replicating.
In the experiments described above and in Figures 3through 7, expression of dengue replicons with heterologous material from HIV was followed either using anti-HIV sera or anti-dengue sera, depending on the experiment.
Evidence that cells continue to replicate and express replicon proteins in both daughter cells after transfection with these chimeric replicons further supports the implication of chimeric replicon replication.
Properly administered, dengue virus replicons expressing HIV epitopes might thus serve as dual vaccines, conferring protection against dengue virus as well as HIV.
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