Words similar to replicative
Example sentences for: replicative
How can you use “replicative” in a sentence? Here are some example sentences to help you improve your vocabulary:
In order to determine if CMV was undergoing an abortive or replicative infection, separate CMV superinfection experiments were performed.
As a result of the absence of sequence overlap between the Adapt plasmid and the Ad5 E1 sequences integrated into the genome of PER.C6, the vector stocks used in this study does not contain replicative competent adenovirus (RCA) [ 35 ] .
In addition to the potential impact of target sequence and secondary structure topology on mutation frequency, other viral replicative proteins including Pol accessory protein, TK, dUTPase, and uracil-DNA glycosylase may cooperate with Pol to modulate polymerase repair and nucleotide selection [ 12 13 19 23 ] .
Recombinant adenovirus vectors were generated in PER.C6™ cells by homologous recombination between an adapter plasmid (pAdapt) and the E1 deleted Ad 5 DNA plasmid as described elsewhere [ 23 ] . As a result of the absence of sequence overlap between the Adapt plasmid and the Ad5 E1 sequences integrated into the genome of PER.C6, the vector stocks used in this study did not contain replicative competent adenovirus (RCA) [ 25 ] . All vectors were produced on PER.C6™ using standard procedures [ 25 ] . Infectious units (iu)/ml were determined by end point cytopathogenic effect (CPE) assay on 911 cells [ 26 ] . Viral particles were determined by HPLC [ 27 ] . The particle to infectious unit ratio was always lower than 5.
During a replicative infection, expression of this protein continues through to the late phase of infection [ 56 ] . One function of the p52 protein is to aid in replication by binding to the viral DNA polymerase.
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