Words similar to reduction-of-function

Example sentences for: reduction-of-function

How can you use “reduction-of-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

The recessive tab mutants are likely to represent reduction-of-function mutations in genes that inhibit exit from mitosis, and the dominant TAB mutants are likely to result from gain-of-function mutations in genes that promote exit from mitosis.
To our surprise, mutations in six linkage groups were uncovered, with three groups being recessive ( tab1-tab3 ) and three groups being dominant ( TAB5-7 ). We have shown in earlier studies that tab2-1 is a reduction-of-function mutation in NET1 (a.k.a.
Mtr10 assembles with and functions as a nuclear import receptor for the mRNA-binding protein Npl3 [ 36 37 ] . Interestingly, srp1-31 also inhibits nuclear import of multiple proteins including Npl3 [ 51 52 ] . Remarkably, reduction-of-function alleles of the karyopherin KAP104 were also recovered in a screen for mutations that suppressed cdc15-2 ts (A.
Formally speaking, it is not possible to order gene functions based on suppressive interactions involving reduction-of-function (e.g.