Example sentences for: reductase

How can you use “reductase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Systematic reviews and recent trials have found that lipid-lowering therapy with HMG co-A reductase inhibitors (statins) can reduce the relative risk of future CHD events by approximately 30% and that this relative risk reduction appears to be similar for patients with different levels of CHD risk.

  • Leber's hereditary optic neuropathy (LHON), the most common cause of male adolescent blindness, is attributed to mutations in mtDNA genes encoding subunits of complex I (NADH dehydrogenase (ND) - alternatively termed NADH CoQ 1 reductase).

  • Among existing drug therapies, 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, more commonly known as statins, provide a generally well-tolerated and effective option for lowering LDL-C levels and decreasing the likelihood of subsequent CHD events [3,4].

  • are catalase and alkyl hydroperoxide reductase.

  • These compounds can activate some nuclear receptors including steroidogenic factor 1 [ 44 ] and LXR, which may be partially responsible for their biological activities [ 45 46 ] . Cholesterol oxides are inhibitors of HMG-CoA reductase, the key enzyme of cholesterol biosynthesis pathway [ 47 ] . The ability to bind to an intracellular receptor, oxysterol binding protein, may be responsible for their inhibition of cholesterol biosynthesis [ 48 49 ] . It should be noted that addition of cholesterol does not prevent cholesterol oxide induced cell death, which leads to the suggestion that inhibition of cholesterol synthesis is not the cause of cholesterol oxide induced PCD [ 50 51 ] . The critical events that result in cholesterol oxide induced cytotoxicity remain to be determined.


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