Words similar to reductase
Example sentences for: reductase
How can you use “reductase” in a sentence? Here are some example sentences to help you improve your vocabulary:
All but the sulfinic and sulfonic acid modifications are readily reversible by reduction, using proteins such as thioredoxin or glutaredoxin; though sulfinic acid reductase activities have recently been identified in yeast and mammalian cells (denoted sulfiredoxin and sestrin, respectively) (Biteau et al.
These authors did not study mRNA levels but reductase activity, therefore, variation at the level of protein stability could also play a role.
These compounds can activate some nuclear receptors including steroidogenic factor 1 [ 44 ] and LXR, which may be partially responsible for their biological activities [ 45 46 ] . Cholesterol oxides are inhibitors of HMG-CoA reductase, the key enzyme of cholesterol biosynthesis pathway [ 47 ] . The ability to bind to an intracellular receptor, oxysterol binding protein, may be responsible for their inhibition of cholesterol biosynthesis [ 48 49 ] . It should be noted that addition of cholesterol does not prevent cholesterol oxide induced cell death, which leads to the suggestion that inhibition of cholesterol synthesis is not the cause of cholesterol oxide induced PCD [ 50 51 ] . The critical events that result in cholesterol oxide induced cytotoxicity remain to be determined.
Amino acid sequences of the confirmed bacterial arsenate reductases (12 total) were initially aligned automatically using the Fast Aligner function of ARB Edit 4.1, and then manually adjusted to ensure that secondary structure considerations of the arsenate reductase protein were met.
The residues in the MIDAS motifs lie on three closely apposed loops located on the upper edge of the β-sheet, where they form the metal-binding site, with oxygen atoms in the aspartate, serine and threonine residues coordinating the metal ion [ 9 ] . In integrin α2β1, which is a collagen receptor, the metal-binding site also binds the collagen ligand through the conserved glutamate in a GFOGER motif (O = hydroxyproline) completing the coordination sphere of the metal [ 28 ] . In vivo, the binding of collagen at this site appears to be regulated through a conformational shift in which the loops forming the MIDAS site change from a closed to an open conformation [ 29 30 31 ] . Other proteins containing a domain with all three MIDAS motifs include the D-subunit of magnesium chelatase [ 32 ] , Ca-activated chloride-channel protein [ 33 34 ] , nitrate reductase (accession AAC79447), and the D subunit of nitric oxide reductase (accession AAC45374).
Loading...