Example sentences for: recombination

How can you use “recombination” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As appealing as the recombination modifier theory of recombination hotspots may be, there is circumstantial evidence that argues against it and that suggests that recombination hotspots are not directly the byproduct of selection on alleles in linkage disequilibrium.

  • Thus, with regard to primary protein sequence (Figure 1), inferred subunit structure (Figure 2and data not shown), strict requirement for meiotic recombination (Figure 2, Table 1), and dependence upon its active site tyrosine (Table 1), Rec12 protein is a structurally and functionally conserved member of the Spo11 family of enzymes that catalyze meiotic dsDNA cleavage to initiate recombination [ 11 ] .

  • A gene is “knocked out” (KO) by homologous recombination of a disrupting piece of DNA within that gene.

  • Recombination within UAU1 to regenerate URA3 eliminates the Bgl II site and results in a cacet1::URA3 locus that would yield an ~5-kbp fragment upon digestion with Bgl II (Figure 1).

  • Previously it has been shown that a targeting vector, pMP8, can correct the loss of Hprt activity in E14TG2a ES cells that lack exons 1 and 2 of the hprt gene [ 2 15 ] . The design of this vector implied that it should also be capable of correcting the hprt exon 1 deficiency in F3 cells and could, therefore, be used to introduce transgenes into the hprt locus by homologous recombination.


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