Words similar to recombinase
Example sentences for: recombinase
How can you use “recombinase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Here integration of the transgene at the gene-trap locus was again mediated by Cre recombinase and translation of the transgene was facilitated by an internal ribosomal entry site (IRES) [ 24].
More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.
The pgk promoter was flanked by loxP elements so that it could be deleted by the action of Cre recombinase.
This suggests that complex patterns underlie the high level of nucleotide diversity observed at individual positions, thereby increasing the specificity of the signal governing recruitment of the V(D)J recombinase.
Briefly, recombinant adenoviruses were generated by homologous recombination in CRE8 cells, a 293 cell line that expresses Cre recombinase, between psi-5, an Ad5-derived, E1- and E3-deleted adenovirus, and pAd-lox, the adenoviral shuttle vector that expresses IL-4.