Example sentences for: recombinase

How can you use “recombinase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Here integration of the transgene at the gene-trap locus was again mediated by Cre recombinase and translation of the transgene was facilitated by an internal ribosomal entry site (IRES) [ 24].

  • More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.

  • The pgk promoter was flanked by loxP elements so that it could be deleted by the action of Cre recombinase.

  • This suggests that complex patterns underlie the high level of nucleotide diversity observed at individual positions, thereby increasing the specificity of the signal governing recruitment of the V(D)J recombinase.

  • Briefly, recombinant adenoviruses were generated by homologous recombination in CRE8 cells, a 293 cell line that expresses Cre recombinase, between psi-5, an Ad5-derived, E1- and E3-deleted adenovirus, and pAd-lox, the adenoviral shuttle vector that expresses IL-4.


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