Example sentences for: recombinase

How can you use “recombinase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This targeting is regulated primarily by binding of RAG1 [ 42], an enzyme in the recombinase complex, to the RSS adjacent to each V, D and J gene segment [ 43].

  • This phylogenetic tree topology resembles that of several proteins involved in core cellular functions such as the DNA recombinase RecA, aminoacyl tRNA synthetases, RNA polymerase and other RNA metabolism proteins [ 21 22 23 ] . This suggests that a CYTH domain was present in the last universal common ancestor of all extant life forms and the extant forms are in part vertically inherited from this ancestral form.

  • More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.

  • An example in the case of the recombinase genes is the loss of recF, which is required for some recA functions [ 38] and which was deleted individually with both flanking genes retained (Table 1).

  • Furthermore, by using modified forms of Cre whose recombinase activity is inducible, one can use these reporter mice to perform detailed analysis on the lineage of cells at different time points during development.


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