Words similar to recombinase
Example sentences for: recombinase
How can you use “recombinase” in a sentence? Here are some example sentences to help you improve your vocabulary:
More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.
This targeting is regulated primarily by binding of RAG1 [ 42], an enzyme in the recombinase complex, to the RSS adjacent to each V, D and J gene segment [ 43].
All of these strains are useful for monitoring the expression of Cre recombinase, as well as for cell lineage tagging experiments [ 9, [ 11 12 13 14 ] ].
TCR, T cell receptor; MHC, major histocompatibility complex; H-2, murine MHC locus; Tag, SV40 T antigen; RIP, rat insulin promoter; RAG, recombinase activating gene.
An example in the case of the recombinase genes is the loss of recF, which is required for some recA functions [ 38] and which was deleted individually with both flanking genes retained (Table 1).
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