Words similar to recombinase
Example sentences for: recombinase
How can you use “recombinase” in a sentence? Here are some example sentences to help you improve your vocabulary:
The pgk promoter was flanked by loxP elements so that it could be deleted by the action of Cre recombinase.
TCR, T cell receptor; MHC, major histocompatibility complex; H-2, murine MHC locus; Tag, SV40 T antigen; RIP, rat insulin promoter; RAG, recombinase activating gene.
Similar Cre reporter strains have been produced using different promoters to express lacZ [ [ 6 7 8 9 ] ], Another variation on this theme has been the development of the Z/AP reporter strain, which switches from lacZ to alkaline phosphatase expression upon exposure to Cre recombinase activity [ 10].
We have constructed two reporter lines of mice that express EYFP or ECFP only in cells expressing the Cre recombinase, and their daughter cells, by targeting these cDNAs into the ubiquitously expressed ROSA26 locus, preceded by a loxP flanked "stop" sequence.
More recently, transgenic mice have also been used to express Cre recombinase to mediate the conditional deletion of loxP -flanked DNA sequences in specific cell types in vivo . Traditional methods for generating transgenic mice require the availability of well characterized transcriptional regulatory elements, promoters or enhancers, that direct transgene expression in specific cell types.
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