Words similar to recbc
Example sentences for: recbc
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[ 26 ] found that both sensitivity to DNA damaging agents and decreased association of crossing-over with double-strand break repair in a recBC sbcA recJ strain are suppressed by mutant recQ alleles.
Accumulation of the huge linear DNAs in the recBC null mutants can be interpreted from the known properties of RecBCD enzyme in a straightforward way.
The mutations in Holliday-structure-processing enzymes - RecG, RuvAB, and RuvC - did not result in accumulation of the huge linears even in the recBC -minus background.
The accumulation of the non-circular, broken chromosomes correlated with the growth rate or DNA damage response in most of the recBC -minus background [ 30 ] . The recB or recC null mutation showed low viability even in the absence of exogenous DNA damage [ 31 32 ] . A simple interpretation of these data is that RecA, RecFOR, and RecQJ functions (and RecET functions for the sbcA background) repair chromosome breakage and/or prevent generation of the breakage.
The accumulation of huge linear DNAs was also seen in other recBC null mutants in this AB1157 genetic background ( recB21 , recC22 and recC73 (Figure 2A)) and in another, V66, genetic background ( recC73 (Figure 2B)), as observed earlier [ 1 2 ] . A recD mutant showed no accumulation.
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