Words similar to rec

Example sentences for: rec

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Identification of four introns (Figure 1) and complete complementation of the rec12-117 hyporecombination defect by the full-length cDNA (Figure 2) confirmed that Rec12 protein is homologous to Spo11 of other eukaryotes [ 11 ] . Both Rec12 and its active site tyrosine are required for intragenic and intergenic recombination at multiple locations on all three chromosomes (Figure 2, Tables 1, 2, data not shown).
The rec12-117 mutant was isolated in a genetic screen; the rec12-117 mutation reportedly confers a 100-fold or greater reduction of intragenic recombination and a 6-fold reduction of intergenic recombination [ 33 ] . To define more precisely the requirement for Rec12 in meiotic chromosome dynamics, we used gene replacement to generate a null ( rec12-D15 ) mutation and a mutation in the putative active site tyrosine ( rec12-Y98F ). We then determined the effects of these mutations upon intergenic (crossover) recombination within intervals of chromosomes
By applying mapping functions for aneuploid meiotic products [ 47 ] , we can set a lower limit of 22% and 29% MII nondisjunction for the rec12-117 and rec12-D15 meioses analyzed, respectively.
Construction of rec12-D15::ura4 +and rec12-Y98Falleles
REC.