Words similar to rdek
Example sentences for: rdek
How can you use “rdek” in a sentence? Here are some example sentences to help you improve your vocabulary:
5a, lanes 9-10) competes only slightly less well than does DQA1*0101 , indicating that a change in the residue at position 7 does not prevent rDEK binding.
Quantitative assessment of rDEK binding to related DQ-and DR- Y-box sequences
5 × 10 4counts per minute) per 15 μl binding reaction and 5 μg of nuclear extract (except as noted) or <1 μg of rDEK.
We have previously shown that activation of promyeloid cells causes dephosphorylation of DEK and diminished DEK binding to the HIV-2 long terminal repeat [ 16 17 32 ] . In this study, we show that rDEK can bind to the DQA1 Y box, and that DEK in nuclear extracts participates in the DQA1 Y-box binding complex in vitro . Thus, we propose a model in which intracellular signaling modulates the ability of DEK to bind DNA, causing alteration of MHC class II transcription.
Having established that DEK and NF-Y in nuclear extracts participate in the HLA-DQA1*0101 binding complex, we used recombinant full-length DEK (rDEK) to determine whether it alone can bind to Y-box motifs and to examine how gene- and allele-specific sequence polymorphisms alter its binding.
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