Words similar to rdek

Example sentences for: rdek

How can you use “rdek” in a sentence? Here are some example sentences to help you improve your vocabulary:

Having established that DEK and NF-Y in nuclear extracts participate in the HLA-DQA1*0101 binding complex, we used recombinant full-length DEK (rDEK) to determine whether it alone can bind to Y-box motifs and to examine how gene- and allele-specific sequence polymorphisms alter its binding.
5 × 10 4counts per minute) per 15 μl binding reaction and 5 μg of nuclear extract (except as noted) or <1 μg of rDEK.
5a, lanes 9-10) competes only slightly less well than does DQA1*0101 , indicating that a change in the residue at position 7 does not prevent rDEK binding.
Finally, DEK binds differentially to specific Y-box sequences found in HLA-DQA1(*0101 and *0501 alleles) and HLA-DRA , consistent with observations of DQA1 gene-specific cell-surface expression [ 36 ] and allele-specific promoter activity [ 33 ] . The specificity of rDEK binding to these and other, related Y-box sequences (including HLA-DQB and HLA-DRB alleles associated with the DR4 haplotype) may correlate with a predisposition to autoim-mune disease seen with certain HLA haplotypes.
The presence and size of rDEK bands were verified by western blotting.