Words similar to rdek

Example sentences for: rdek

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Further characterization of rDEK binding to the polymorphic DQA1*0501 Y-box sequence and to the consensus ( HLA-DRA ) Y-box sequence establishes a relative hierarchy of DEK binding activity (Fig.
5a, lanes 9-10) competes only slightly less well than does DQA1*0101 , indicating that a change in the residue at position 7 does not prevent rDEK binding.
We have previously shown that activation of promyeloid cells causes dephosphorylation of DEK and diminished DEK binding to the HIV-2 long terminal repeat [ 16 17 32 ] . In this study, we show that rDEK can bind to the DQA1 Y box, and that DEK in nuclear extracts participates in the DQA1 Y-box binding complex in vitro . Thus, we propose a model in which intracellular signaling modulates the ability of DEK to bind DNA, causing alteration of MHC class II transcription.
Quantitative assessment of rDEK binding to related DQ-and DR- Y-box sequences
The HLA-DQA1*0101 Y-box sequence does bind rDEK specifically, with unlabeled probe sequence competing successfully for binding (Fig.