Words similar to rb
Example sentences for: rb
How can you use “rb” in a sentence? Here are some example sentences to help you improve your vocabulary:
If the idea that transcription strength mainly drives Tag expression is kept as the working hypothesis, then there are at least three possibilities to explain the K1 data: 1) the K1 protein has a mildly shorter half-life and the small difference results in a different phenotype vis-à-vis the density related expression; 2) failure to bind Rb family members significantly affects the half-life during exponential growth; 3) the LTR vectors can occasionally display integration position effects that in this special case was subject to density dependent control that is different from most LTR driven cell populations.
To date, heterozygous inactivation of any of the other tumor suppressor genes implicated in breast cancer, including P53, Brca1, Brca2 , and Rb , has failed to cooperate with Wnt-1 in promoting the appearance of mammary tumors [reviewed in ref.
Upon treatment with 2.5 μM SAHA for 24 h, a profound increase in hypophosphorylation of the three pocket proteins was observed in both TM10 and to a lesser extent in TM2H cells as compared with their control counterparts, judged by the faster mobility of the Rb pocket protein isoforms on SDS gel (Fig.
Although SAHA increases acetylation of histones H3 and H4, it is not known whether SAHA is able to inhibit all HDAC activities of all types of histones, including HDAC1, or whether the profound increase in Rb2/p130-E2F-4 nuclear complex after SAHA treatment may have an alternative pathway other than recruitment of HDAC1 activity.
Protein (250 μg) from the control-infected or HIV-1-infected podocytes on day 14 of the differentiation protocol was also analyzed by western blot for total pRb (ECL detection of a 1:1000 dilution of rabbit anti-Rb, Santa Cruz Biotechnology) and phospho-Rb (Ser780) (ECL detection of a 1:500 dilution of rabbit anti-phospho-Rb (Ser780) antibody binding, Cell Signaling).