Example sentences for: raf

How can you use “raf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The latter is consistent with the demonstration that c-Raf function is not mediated by the MAPK/ERK cascade [ 59 ] . Moreover, although we find an increase in total Raf protein (Table 2), no increase in activated c-Raf is found; we also see a 2-fold increase in activated Caspase 3 but no change in total Caspase 3 protein.

  • Viewing the most defining proteins with altered expression, it is clearly reflective of increased apoptosis (increased Chk1, Caspase 6, E2F1), decreased cell proliferation and branching (decreased GR), and, interestingly, increased expression of diverse signal transduction pathways (Ras/Raf/ERK, JNK) to compensate for the proapoptotic signal.

  • Specifically, we evaluated the levels of activated c-Raf, ERK1/2, Caspase 3, and PARP using antibodies which identify only the phosphorylated or cleaved proteins and do not cross react with the inactive protein.

  • RAS activates a cascade of kinases, including RAF, MAP kinase kinase (MEK) and MAP kinase.

  • Precipitation against Raf1 and analysis for p21 Rasfollowed.


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