Example sentences for: radioligand

How can you use “radioligand” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • B max (receptor density) and K d (radioligand affinity) values were determined from the analyses of saturation experiments utilizing nonlinear regression with Prism 3 (GraphPad, San Diego, CA).

  • For saturation experiments, the resulting pellet (a crude particulate membrane fraction) was resuspended in 200 volumes of 25 mM NaPO 4 buffer (pH 7.4) and re-homogenized for use in the radioligand binding assay.

  • Nonspecific binding, calculated from reactions with an excess of unlabeled ligand (100-fold) over radioligand, reached about 40% of the total binding.

  • Radioligand Binding Assay

  • Our results agree with in situ studies in human skin, where macrophages also express binding sites for radiolabelled CCL3, CCL5 and CXCL8 [ 24 25 ] . The disadvantage with the radioligand technique is the lack of definition regarding the molecular nature of the receptors.


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