Example sentences for: purifying

How can you use “purifying” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Here we present a simple model, based solely on purifying selection and mutation at the nucleotide level, that quantitatively predicts both codon and amino-acid usage trends across archaea, bacteria and eukaryotes on the basis of the genome GC content.

  • The observation that K n << K s for most of the recently diverged paralogs is, in itself, not sufficient to conclude that both paralogs in each pair are subject to purifying selection.

  • Third, the possibility exists that, even if many of the observed interactions are functionally important and, by inference, the respective binding sites are subject to purifying selection, the binding sites for different partners tend to overlap such that the number of amino residues in these sites increases only slowly with the increase in the numbers of interactions.

  • In order to avoid purifying antibodies to the 6-His tag in III1-C, the affinity column was made with a GST fusion protein.

  • Combining this information with the observations that recently duplicated genes evolve under purifying selection ([ 21] and our present work), it seems reasonable to hypothesize that a majority of duplicated genes that achieve fixation in a population increase fitness when present in two or more copies in a genome and thus are subject to purifying selection from the moment of duplication.


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