Example sentences for: purifying

How can you use “purifying” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, the observation that purifying selection appears to act on all recent duplicates and examination of the functions of recently duplicated genes do not support the notion that gene duplication results in true functional redundancy and duplications may achieve fixation despite being redundant [ 26].

  • Furthermore, a study of 17 pairs of duplicated genes in the tetraploid frog Xenopus laevis has shown that both copies were subject to purifying selection [ 9], contrary to the notion of neutrality of one of the copies [ 1].

  • The observation that K n << K s for most of the recently diverged paralogs is, in itself, not sufficient to conclude that both paralogs in each pair are subject to purifying selection.

  • In general, however, only a small fraction of sites in some genes appears to evolve under positive selection [ 15], and relaxation of purifying selection is likely to be the main mechanism behind the acceleration of evolution after duplication.

  • A recent genome-wide analysis of duplicated genes of eukaryotes has suggested that they evolve under purifying selection, with an apparent early phase of relaxed constraint or even near-neutrality [ 21].


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