Example sentences for: profoundly

How can you use “profoundly” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ISA became progressively more severe, profoundly affecting all eyes by 23 months (Table 1, Figure 1).

  • In the lens, alpha-crystallin also forms a complex with type III intermediate filament proteins and the lens-specific beaded filament proteins CP49 and CP115, which may be critical for proper filament assembly [ 16 ] . Beaded filament mRNA levels increase greatly in differentiating lens epithelial cells, and have been suggested as a pan-specific marker for lens fiber cells [ 17 ] . It is therefore possible that increased synthesis of alpha-crystallin in epithelial cells early in the differentiation process may have profound effects upon the cytoskeleton, which in turn may profoundly affect cell shape and migration.

  • The nearest municipality is 90 miles away, and outsiders are profoundly unwelcome.

  • “The Brundtland report celebrated by many at Globe '90, while hard-hitting in its analysis of the global environmental crisis, is profoundly shallow in its prescriptions.”

  • 5are consistent with this conclusion: adeno-RGS3 infection of rat pituitary cells profoundly suppressed GnRH-stimulated 3H-inositol phosphate accumulation.


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