Words similar to profound

Example sentences for: profound

How can you use “profound” in a sentence? Here are some example sentences to help you improve your vocabulary:

The reforms that have been adopted so far have profound implications for what government does, how it is organized, and how it performs its services to the country and its citizens.
Gore Vidal ("the consummate pseudo-intellectual who disguises his bilious prejudices as profound insight," writes David Greenberg);
Addition of a complex cRNA background elicited a profound effect on observed intensities, especially at the lower range of concentration.
In ischemic stroke, the most common type, a profound disturbance of focal cerebral blood flow leads to irreversible parenchymal injury.
Complete electrical silence occurs with profound hypothermia (7-20°c) [ 22].