Words similar to profound

Example sentences for: profound

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On a population basis, the effect may be profound; sensitization to cats among school-age children is generally ~10%, while mite sensitization is often as high as 30% (Figure 2).
The most profound form of T-cell tolerance involves deletion of potentially self-reactive T cells during thymic selection.
This is an important new area of research that could conceivably lead to more physiological sleep aids than are currently available, with profound implications for improved public health.
Complete electrical silence occurs with profound hypothermia (7-20°c) [ 22].
Rag -/-mutants have a profound thymocyte development block at the TN3 to TN4/preDP transition [ 51 ] . During normal wild type fetal thymus development, significant DP cell development does not occur until E16.