Words similar to profound

Example sentences for: profound

How can you use “profound” in a sentence? Here are some example sentences to help you improve your vocabulary:

is received with profound indifference’ and that “the hardest words of lay critics from Swift to date ...
It is likely that the difference in turnover of sα i2 and α i2 is even more profound when the proteins are expressed at lower levels.
The effect of SAHA was profound on the nuclear PCNA fraction in both cell lines, but minimal on the cytoplasmic PCNA fraction.
When Miller says that the "most profound sentimental basis" of rock is nostalgia , I hear not a critical insight but the moaning of one who's, like the rest of us, getting old.
Current saving and investment decisions have profound implications for the nation's level of well-being in the future.