Words similar to profound

Example sentences for: profound

How can you use “profound” in a sentence? Here are some example sentences to help you improve your vocabulary:

Your e-mail--and the cultural elite's obsession with the The Sopranos --reminds me of Angie's profound comment.
The papers all note that the votes came just minutes after another Clinton apology, this time from the White House Rose Garden, in which he expressed profound regret, asked for a censure from Congress, and, once again, did not admit to lying under oath.
a profound desire not to make what he does look costly to him, emotionally or intellectually."
Nevertheless, the discoveries about the role of the insulin/IGF-1 pathway in ageing have had a profound impact on her own lifestyle, which includes a tendency to discard the bread from sandwiches and eat only the toppings of pizzas (Box 2).
Immuno-staining for ACTH in the pituitary showed no profound difference due to LIFR loss (Figure 4Aand 4B).