Example sentences for: prla

How can you use “prla” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Deletion of the signal sequence from phoA severely compromises export; export is restored in a prlA suppressor strain.

  • The in vivo results are founded both on the co-immunoprecipitation experiments and on the fact that no export of the protein was detected in a prlA4 strain, while the in vitro results are based on the protease protection assays.

  • The PrlA (SecY) and PrlG (SecE) suppressors are compromised in their ability to proofread, allowing export of proteins with mutations, or even complete deletions, of the signal sequence.

  • In fact, all of the PrlA and PrlG suppressors are completely dependent on functional SecB for manifestation of suppressor activity [ 5 8 ] . Even certain proteins that are not normally SecB-dependent for translocation become SecB-dependent when they contain a signal sequence mutation and are exported via the suppressor pathway.

  • In the secY wild type strain, proofreading by SecE/Y would block export of LA57-N 102LT, while in the prlA4 strain, the PrlA4 suppressor would allow export of a portion of LA57-N 102LTto the periplasm.


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