Words similar to pparδ

Example sentences for: pparδ

How can you use “pparδ” in a sentence? Here are some example sentences to help you improve your vocabulary:

2004) reveals that a peroxisome proliferator-activated receptor δ (PPARδ)-mediated transcriptional pathway is involved in the regulation of the skeletal musclefiber phenotype.
PPARs are nuclear hormone receptors that are activated by micromolar concentrations of various FAs and FA analogues, such as fibrates and thiazolidinediones [ 29 ] . This subfamily can be divided into three isotypes, designated PPARα, PPARδ and PPARγ, each with tissue-specific expression.
Thus—through functional genomics—calcineurin, calmodulin-dependent kinase, PGC-1α, and activated PPARδ form the basis of a signaling network that controls skeletal muscle fiber-type transformation and metabolic profiles that protect against insulin resistance and obesity.
PPREs are direct repeats (DR) of a hexanucleotide sequence AGGTCA separated by one nucleotide and are therefore referred to as a DR-1 response element [ 30 ] . PPARα and PPARγ play critical roles in the catabolism and storage of FA, whereas the function of PPARδ is less certain.
Moreover, functional genomics support the concept that skeletal muscle remodeling to a ST phenotype, either through activated calcineurin or PPARδ, can protect against the development of dietary-induced insulin resistance (Ryder et al.