Words similar to pparγ
Example sentences for: pparγ
How can you use “pparγ” in a sentence? Here are some example sentences to help you improve your vocabulary:
While 15d-PGJ 2 is considered to be a PPARγ agonist, indomethacin and ibuprofen can activate both PPARγ and PPARα [ 27 ] . The following experiment was conducted to determine if a pure PPARα agonist, WY14643, could modulate the 25-OH-cholesterol induced cytotoxicity.
Many naturally occurring or synthetic compounds are agonists for the PPARs [ 20 21 ] . For example, a number of prostaglandins are agonists for PPARγ . The prostaglandin, 15-deoxy-delta 12, 14-PGJ 2 (15d-PGJ 2 ), is the most potent endogenous PPARγ agonist known.
In the case of the PPARγ/RXR complex, for example, activation with PPAR or RXR specific ligands results in recruitment of quite different coactivators [ 19 ] .
Cells were pretreated with the PPARγ agonist 15d-PGJ 2 overnight followed by H 2 O 2 for one day (without 15d-PGJ 2 ) and processed for the MTT viability assay.
This study was designed to examine morphological alterations in RPE during oxidative stress, the involvement of ERK MAP kinase and 4-HNE and to test the hypothesis that PPARγ activation can prevent oxidative damage on RPE cells.