Example sentences for: pparγ

How can you use “pparγ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Even though H 2 O 2 did not increase PPARγ protein expression significantly as indicated in the previous study, experiments were performed to determine whether PPARγ agonists could activate the existing PPARγ thus preventing H 2 O 2 induced cytotoxicity in RPE cells.

  • Prevention of oxidative stress induced cytotoxicity by PPARγ agonists

  • For example, PPARγ agonists were shown to protect cytokine-induced PCD in cerebellar granule cells [ 59 ] . These agents could also block the neurotoxic effects caused by β-amyloid activated microglia, and thus might be beneficial in the treatment of Alzheimer's disease [ 60 ] . In non-neuronal tissues, PPARα activation was shown to suppress both spontaneous rat hepatocyte PCD and the PCD induced by transforming growth factor-β1 [ 61 ] .

  • During rod outer segment ingestion, there is a generation of H 2 O 2 [ 2 3 ] and an up-regulation of PPARγ mRNA expression [ 24 ] in RPE, experiments were performed to determine if H 2 O 2 could induce PPARγ protein expression over the control levels.

  • Cells were pretreated with the PPARγ agonist 15d-PGJ 2 overnight followed by H 2 O 2 for one day (without 15d-PGJ 2 ) and processed for the MTT viability assay.


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