Words similar to position-weight
Example sentences for: position-weight
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(b) Position Weight Matrix Methods (PWM) to scan known binding sites: We have prepared position-weight matrices [ 15 ] of those Arabidopsis transcription factors for which at least 5-10 experimentally known binding sites exist.
For example, the binding sites for Mcm1p and Rap1p are poorly modeled by exact words, in that these transcription factors bind sequences with relaxed specificity at certain positions [ 11 ] . Our method missed examples of multifactorial regulation involving Mcm1p or Rap1p that were suggested by previous work using position-weight matrices [ 17 ] . In addition, our method required sequence identity for a word to be labeled as conserved.