Example sentences for: polyq

How can you use “polyq” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This fusion polypeptide efficiently formed prion [F + ]. Furthermore, when the oligopeptide repeat sequence was added to a polyQ sequence, this fusion polypeptide also acquired the ability to form self-propagating aggregates.

  • Even if a protein with a polyQ domain does not form a prion, its aggregation may depend on certain prions.

  • Importantly, aggregates formed by polypeptides with the Q/N-rich or polyQ domains are not necessarily self-propagating aggregates, i.e., prions.

  • Such expansion of the polyQ domains in certain neuronal proteins could cause neurodegenerative disorders, e.g., Huntington's disease or several forms of ataxia.

  • Some of the Q/N-rich or polyQ domains facilitate aggregation of polypeptides, especially if expanded owing to mutations.


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