Words similar to polo-like

Example sentences for: polo-like

How can you use “polo-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

In S. cerevisiae , disassembly of the RENT complex and the subsequent release of Cdc14 from the nucleolus drive cells to exit mitosis [ 8 9 ] . This event is thought to require two independent signals: an unknown mitosis-specific signal and a signal from the mitotic exit network (MEN) proteins including Tem1, Cdc15, and Dbf2 [ 8 9 ] . The Polo-like kinase Cdc5 also belongs to the MEN, thus we tested whether it too is required for release of Cdc14 from the nucleolus by using indirect immunofluorescence to compare Cdc14 localization patterns in wild type and cdc5-1 cells.
Thus, we surmise that Polo-like kinase disassembles RENT in vitro by eliminating the Cdc14-affinity of Net1.
extracts, phosphorylation of cohesin also depends on Polo-like kinase, and this phosphorylation reduces the ability of cohesin to bind to chromatin [8].
Depletion of Cdc5 or Polo-like kinase in cdc5▲ cells arrests a significant fraction of the cells in early anaphase with short mitotic spindles [ 20 21 ] , and phosphorylation of the cohesin subunit Scc1 by Cdc5 enhances the efficiency of Scc1 cleavage by the separase Esp1 during the metaphase to anaphase transition [ 22 ] .
If Cdc5 disassembled the RENT complex through phosphorylating Net1, then a mutant Net1 lacking Cdc5 phosphorylation sites should bind Cdc14 even in the presence of active Cdc5/Polo-like kinase.