Words similar to pneumococcal

Example sentences for: pneumococcal

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The hypothesis that protection from invasive pneumococcal disease is caused by the acquisition of anticapsular antibodies directed against each of the pneumococcal serotypes yields two simple predictions about the age-specific epidemiology of pneumococcal disease.
A study was recently carried out at the University of Minnesota, applying radioactively labeled cDNA microarrays [ 14] to the mRNA analysis of 1,176 genes in middle-ear mucosa of rats with and without subacute pneumococcal middle-ear infection.
Since most individuals do not suffer from invasive pneumococcal disease in this age range, carriage or mucosal disease (otitis media) from pneumococci may be the immunizing event for anticapsular antibodies in the general population [12] (although in principle immunity to some serogroups could be generated in response to cross-reacting antigens from other bacterial species or other sources [14]).
The likelihood that mechanisms other than anticapsular antibody confer immunity to pneumococcal disease has important implications with respect to vaccine design.
Studies of pneumococcal carriage do show gradual changes in the prevalence and serotype composition of the nasopharyngeal flora in these years, but the prevalence of carriage changes much more gradually than the incidence of invasive disease [29].