Example sentences for: pneumococcal

How can you use “pneumococcal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Figure 1 shows the age-specific incidence of invasive pneumococcal disease, by capsular serogroup, obtained from population-based active surveillance in the United States prior to the introduction of the conjugate vaccine.

  • We are not aware of data that bear strongly on the plausibility of other possible mechanisms for the age-related decline in pneumococcal disease, such as changes in anatomy, physiology, receptor expression, or resident bacterial flora.

  • As experience with conjugate pneumococcal vaccines in children unfolds, it is becoming increasingly clear that such a strategy suffers from several limitations, including the possibility of serotype replacement (already confirmed in several clinical trials), a modest effect on nasopharyngeal colonization, limited serotype coverage, cost, and difficulties in production that have led to shortages since licensure.

  • Data were not available on the timing of anticapsular antibody acquisition in these same populations, but we compared the timing of the decline in pneumococcal disease against previously published data on age-specific prevalence of anticapsular antibody levels greater than 0.2 mcg/ml [9].

  • Although we suggest that anticapsular antibody is not primarily responsible for the age-specific decline in invasive pneumococcal disease, there is no question that the capsule is an important virulence factor that interacts with the innate and acquired immune system in a number of ways.


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