Example sentences for: pkcα

How can you use “pkcα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The blots show that PKCα, the major PKC isoform present in muscle, is not detected by the PKCβII antibody, and that there is little overlap between the specificities of the PKA regulatory subunit antibodies.

  • PKCβ labeling in the muscle fibers is faint, which corroborates the report that PKCα and PKCθ are the predominant PKC isoforms in skeletal muscle [ 24 ] , with PKCθ being more abundant in the membrane fraction of muscle and PKCα being more abundant in the cytosolic fraction.

  • PKCβ was shown to localize to the presynaptic terminals of NMJs [ 22 23 ] , whereas PKCθ plays a postsynaptic role at the NMJ [ 24 ] . In skeletal muscle, PKCα was found in human muscle fibers [ 25 ] and with T-tubules in rabbit skeletal muscle [ 26 ] . However, it is unknown whether tethering to a PKC-anchoring protein mediates the localization to these compartments.

  • We have previously reported that retinal CaMKII mRNA, protein and enzyme activity (localized in the somas of amacrine cells and ganglion cells and in the inner plexifom layer) but not PKCα (localized in bipolar cells) are increased in the rdta mouse [ 34].

  • 7), consistent with enhanced PKCα and PKCθ labeling in the NMJ [ 24 ] . Over a background of more diffuse staining, two stronger bands can be observed.


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