Example sentences for: pip

How can you use “pip” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Phosphatidylinositol-(3,4,5)-trisphosphate (PIP3) is one of the major intracellular second messengers regulating growth, metabolism and vesicular trafficking [for reviews see refs [ 1 2 3 ] ]. The level of (PIP3) in the cell is determined by the balance of kinase and phosphatase activity.

  • In similar experiments using mixed PIP 2 /PC vesicles, all of the Boi1-PH stayed in the soluble fraction (data not shown), supporting the views that the composition of the lipid bilayer affects the ability of Boi1-PH to bind PIP 2 and that PS promotes this association.

  • (In this and all subsequent experiments that use PIP 2 /PS mixed vesicles, the mass ratio of PIP 2 :PS was 1:20.)

  • In this analysis, we asked whether an otherwise soluble fraction of Boi1-PH, after being incubated with PIP 2 -bearing vesicles, would now sediment in conditions (436,000 × g for 1 hr) that cause vesicles to pellet.

  • 3, lanes 3-8), suggesting that Boi1-PH has a higher affinity for PIP 2 than for PS.


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