Words similar to pioneered
Example sentences for: pioneered
How can you use “pioneered” in a sentence? Here are some example sentences to help you improve your vocabulary:
This approach had been pioneered in the classical work of Dobzhansky and Sturtevant who used inversions in Drosophila chromosomes to construct an evolutionary tree [ 12 ] . Subsequently, mathematical methods have been developed to calculate rearrangement distances between genomes, and, using these, phylogenetic trees have been built for certain small genomes, such as plant mitochondria and herpesviruses [ 13 14 ] . These approaches, however, are applicable only to genomes that show significant conservation of global gene order, which is manifestly not the case among prokaryotes [ 15 16 17 ] . Even relatively close species such as, for example, Escherichia coli and Haemophilus influenzae, two species of the γ-subdivision of Proteobacteria, retain very little conservation of gene order beyond the operon level (typically, two-to-four genes in a row), and essentially none is detectable among evolutionarily distant bacteria and archaea [ 15 16 18 ] . Very few operons, primarily those coding for physically interacting subunits of multiprotein complexes such as certain ribosomal proteins or RNA-polymerase subunits, are conserved across a wide range of prokaryotic lineages [ 15 16 ] . On the other hand, pairwise comparisons of even distantly related prokaryotic genomes reveal considerable number of shared (predicted) operons, which creates an opportunity for a meaningful comparative analysis [ 19 ] [ 20 21 ] .
When Sam Donaldson pointed out on This Week that two Republicans, President Richard Nixon and Secretary of State Henry Kissinger, had pioneered engagement in the Shanghai Communiqué, George Will exploded: "I was for impeaching Nixon over the Shanghai Communiqué!"
Coburn pioneered two major and highly successful programs in New Jersey.
As for AIDS, the new treatments--mainly pioneered in the US by big drug companies trying to make profits, not do good--are far cheaper than the alternative of doing nothing and so economics should and will guarantee that most people who need them (and can take them responsibly) should get them.
These two pillars of legal education--the so-called "Socratic method" and the "case method"--were both pioneered at Harvard and survive there less changed than anywhere else.
Loading...