Example sentences for: phosphodiesterases

How can you use “phosphodiesterases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • They are likely to function as sensors of diffusible gaseous ligands that activate at least three distinct, downstream signaling pathways: namely phosphotransfer through the two-component systems, methyl ester-dependent chemotactic response and cyclic nucleotide signaling through the diguanylate cyclases/phosphodiesterases.

  • Genes encoding practically all the solo versions of the HNOB domain occur in the same predicted operon as a histidine kinase or a GGDEF domain (diguanylate cyclase) [ 33 34 35 ] . In some cases these operons also encode receiver domain proteins of the two component systems, PP2C phosphatases or cyclic diguanylate phosphodiesterases (Fig.

  • The bacterial solo versions co-occur in predicted operons encoding genes for two component systems and diguanylate cyclases or phosphodiesterases, and are likely to transmit signals to these downstream molecules.

  • cAMP is an important signaling molecule that can be found in specific cellular domains [ 53 ] . Levels are controlled through synthesis via adenylate cyclase, and degradation via phosphodiesterases (PDEs).

  • In such a scenario it could participate in allosteric regulation of the SGCs, similar to the GAF domains of the cyclic nucleotide phosphodiesterases [ 6 13 ] .

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