Words similar to phe
Example sentences for: phe
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Values for f2 (the percentage of identical codons for conserved twofold-redundant amino acids - Cys, Asp, Glu, Phe, His, Lys, Asn, Gln, and Tyr) between two aligned proteins are calculated by looking at the codons' third position in positions at which amino acids with twofold degeneracy occur.
The consensus codon is given as ttt (Phe; Table 1, column 1).
predicted that Phe158 and Ile 164 form hydrophobic interactions with bulky substituents on the substrate, suggesting that the loss of these residues would only affect binding of substrates with large aromatic substituents [ 37 ] . In the modeling studies on CcrA [ 42 ] , Asn233 was predicted to interact with the β-lactam carbonyl on substrate, and mutagenesis studies have supported this prediction [ 43 ] . Although Asn233 is sequence conserved in L1 [ 35 ] , it is located 14Å away from the modeled position of the β-lactam carbonyl and was predicted not to play a role in substrate binding to L1 [ 37 ] . On the other hand, the substrate-binding model predicted that Tyr228 was in position to offer a hydrogen bond to the β-lactam carbonyl and participate in an oxyanion hole that was proposed to form as the substrate was hydrolyzed [ 37 ] . By using the crystal structure and modeling studies on L1, Ullah et al.
Alexa 488 and BODIPY TR were used to label dermorphin, deltrophin, TIPP (Try-Tic-Phe-Phe) and endomorphin by adding a cysteine to each peptide at the C-terminus, followed by conjugation of the fluorophores to the cysteine residue.
For example, steric hindrance caused by substitution of bulky Phe for Gly78 (residue numbers are given with reference to Lhcbl) in the position designated a 6 [ 29 ] prevented this peptide carbonyl, non-H-bonded because of Pro82 one helical turn further, from serving as a ligand (see Fig.
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