Words similar to phe
Example sentences for: phe
How can you use “phe” in a sentence? Here are some example sentences to help you improve your vocabulary:
The p51 subunit is generated via endoproteolytic cleavage of the p66 subunit between Phe 440 and Tyr 441 [ 5 6 ] . The larger subunit (p66) contains both polymerase and RNase H activities, while the smaller subunit (p51) lacks these functions, in context of the heterodimer [ 7 8 ] . However, both the p66 and p51 monomers are functionally inactive when dissociated from each other [ 9 ] . Several years have passed since it was first suggested that agents that could specifically disrupt the dimerization of HIV-1 RT might prove a worthwhile antiretroviral strategy [ 10 ] , though such agents have yet to be developed.
For example, steric hindrance caused by substitution of bulky Phe for Gly78 (residue numbers are given with reference to Lhcbl) in the position designated a 6 [ 29 ] prevented this peptide carbonyl, non-H-bonded because of Pro82 one helical turn further, from serving as a ligand (see Fig.
B. subtilis genes dap, lys, phe and thr (n = 96 = 4 × 24) [ 29 30 31 ] .; for reviews about current normalization strategies see [ 10 23 ] .
predicted that Phe158 and Ile 164 form hydrophobic interactions with bulky substituents on the substrate, suggesting that the loss of these residues would only affect binding of substrates with large aromatic substituents [ 37 ] . In the modeling studies on CcrA [ 42 ] , Asn233 was predicted to interact with the β-lactam carbonyl on substrate, and mutagenesis studies have supported this prediction [ 43 ] . Although Asn233 is sequence conserved in L1 [ 35 ] , it is located 14Å away from the modeled position of the β-lactam carbonyl and was predicted not to play a role in substrate binding to L1 [ 37 ] . On the other hand, the substrate-binding model predicted that Tyr228 was in position to offer a hydrogen bond to the β-lactam carbonyl and participate in an oxyanion hole that was proposed to form as the substrate was hydrolyzed [ 37 ] . By using the crystal structure and modeling studies on L1, Ullah et al.
For example, if the consensus codon at a protein position were ttt (Phe), QUASI would test the R:Ss of all point mutations from ttt.
Loading...