Example sentences for: phagosome-lysosome

How can you use “phagosome-lysosome” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mycobacteria enter macrophages primarily by conventional receptor-mediated phagocytic pathways [ 3 ] . Following phagocytosis, phagosomes containing viable tubercle bacilli fail to acidify, apparently because of failure to insert a proton-ATPase pump into the phagosomal membrane [ 4 5 6 ] . This leads to altered vacuolar maturation such that phagosome-lysosome fusion is blocked and the mycobacteria-containing vacuoles end up with an internal pH of about 6 and markers of phagosomes and early and late endosomes [ 7 8 9 10 11 ] . The mycobacterial genes responsible for these processes are largely unknown.

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