Example sentences for: permeable

How can you use “permeable” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Early in the process the outer membrane becomes permeable, without rupture (Although this is controversial [ 27 ] .), to several proteins found in the mitochondrial inner membrane space including cytochrome c, in which contact sites have a probable role [ 28 ] . During this early phase, though, the inner membrane remains intact and mitochondria still retain their protein import machinery [ 29 ] . Later in the process there is swelling and herniation of the matrix leading to a distension of the cristae [ 8 30 ] .

  • For analysis of intracellular CTLA-4, spleen cells were first stained with the above fluorescence-labeled antibodies, fixed and rendered permeable, and stained with R-phycoerythrin (PE)-labeled anti-CTLA-4 using a Cytofix/Cytoperm kit (BD PharMingen).

  • The initial MTX-induced increase in [Ca 2+] i reflects the activation of a Ca 2+-permeable non-selective cation channel (CaNSC) [ 1 4 5 6 7 8 ] . This channel, which has a reported conductance in the range of 12-40 pS depending on ionic conditions [ 5 9 10 11 ] , causes rapid membrane depolarization, which in excitable cells, leads to activation of voltage-sensitive channels.

  • In each of the enumerated studies, a minimum of 12 explants were cultured for 2 or 4 days in the cell permeable peptide SN50 (Biomol Research, Plymouth Meeting, PA) which inhibits NF-κB translocation into the nucleus [ 24 33 34 35 ] . The concentration used (100 μg/ml) was double that shown to inhibit NF-κB translocation in mouse endothelial LE-II cells; 100 μg/ml mutant SN50 (mSN50) peptide was used as a positive control and control BGJb medium as a negative control.

  • On the other hand, it has been previously demonstrated that direct activation of adenylate cyclase by Forskolin or cholera toxin, inhibition of cAMP-specific phosphodiesterase, and treatment with a cell permeable cAMP analog, induces a rise in intracellular cAMP [ 22 23 24 25 26 ] . Since cAMP is known to modulate the expression of CD8 in mice [ 27 ] , we sought to determine whether cAMP-dependent protein kinase (PKA)-mediated signaling plays a role in modulating the mRNA levels of CD3, CD4, and CD8 in ex vivo examined human thymocytes.


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