Words similar to permeable
Example sentences for: permeable
How can you use “permeable” in a sentence? Here are some example sentences to help you improve your vocabulary:
For the P2X receptor it has been suggested that the Ca 2+-permeable channels grow in size to form the dye-permeable pores through either aggregation of channel subunits or through dilation of the existing channel pore structure [ 12, 18, 19, 20, 21].
This occurs, not by release of Ca 2+from internal stores, but rather from activation of a ubiquitously-expressed, non-selective, Ca 2+-permeable cation channel (CaNSC), present in the plasmalemma [ 2, 3, 4, 5, 6, 7, 8].
They are constitutively permeable to water, and also function as regulated non-selective cation channels [ 10 ] when gated by intracellular cyclic GMP [ 11 12 ] . Even though only a small proportion of the AQP1 channels that are present in the membrane appear to be available for cGMP-activation of the ionic conductance (1/56,000), model-based calculations nonetheless suggest that this contribution could be meaningful in a physiological setting [ 13 ] . Unlike transporters which move substantial amounts of substrate by design, ion channels function to change membrane potential by the net movement of relatively tiny amounts of charge (~10 picomoles per cm 2membrane to generate a change of 100 mV) [ 14 ] , hence the low proportion of active AQP1 ion channels is consistent with a functional goal of gated ionic signaling that is distinct from that of massive constitutive osmotic water permeability.
In contrast to the non-NMDA receptors, the high conductance channel associated with the NMDA receptors is permeable to Ca 2+as well as to Na +and K +. Also NMDA-gated currents typically have slower kinetics than kainate- and AMPA-gated channels [ 3].
To evaluate the relevance of the experimental results obtained using PGC-2, we examined the effect of 4-AP on the progesterone output of primary GC cultures supplemented with either the membrane permeable cAMP analog, 8-(4-chlorophenylthio) adenosine-3',5'-cyclic monophosphorothioate (8-CPT-cAMP, 1 mM) or estradiol 17β (500 ng/ml).
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