Words similar to peripubertal
Example sentences for: peripubertal
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In contrast, SD had a greater effect on testis size in peripubertal males (55% smaller testis volume in SD than LD; Fig 3) than in adult males (15% smaller testis volume in SD than LD; Fig.
The large difference between the SD and LD groups in peripubertal males was caused by the rapid rate at which testes of the LD group were growing compared to a slow rate of growth in the SD group.
Recent reports have documented variability in photoresponsiveness in peripubertal males among laboratory rat strains [ 5 6 ] . The fact that photoresponsiveness extends to adulthood in F344 rats suggests that genetic variation in the presence and strength of adult photoresponsiveness is present among rat strains.
However, recent work shows that laboratory rat strains vary in their responsiveness to photoperiod [ 3 4 5 6 ] . Laboratory rats of some strains can be manipulated to unmask responses to photoperiod or melatonin, even though short photoperiod alone does not affect reproduction [ 7 8 9 ] . Peripubertal rats in the inbred Fischer 344 (F344) and Brown Norway (BN) strains are naturally sensitive to reproductive inhibition by short photoperiod alone [ 4 5 6 ] . In several species of rodents, peripubertal young have stronger reproductive responses to photoperiod than adults [ 10 11 12 13 ] , and this appears to be true for induced-photoresponsive laboratory rats as well [ 14 ] .
The proportionately larger effects of SD on peripubertal males are consistent with the hypothesis that young animals are more sensitive to seasonal reproductive inhibition than adults [ 10 11 12 13 ] . The reductions in testis size of adult rats in SD were slight, and might, by itself, have negligible effects on fertility in adult rats.
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