Words similar to peripheral
Example sentences for: peripheral
How can you use “peripheral” in a sentence? Here are some example sentences to help you improve your vocabulary:
Acute bladder inflammation induced by local (intravesical) administration of chemical irritants or lipopolysaccharide altered the levels of this cytokine in the bladder suggesting that MIF may be implicated in the early stages of bladder inflammation [ 10 11 ] . In addition, there were changes in the levels of MIF and cyclooxygenase-2 in the central and peripheral nervous tissues that innervate the bladder and other pelvic viscera.
Except for significantly decreased expressions of CCR5 and CXCR4, there were no differences between chemokine receptor expressions by synovial tissue and peripheral blood CD4 +memory T cells.
The postoperative category 'peripheral vascular surgery', which is associated with a low mortality risk (APACHE II diagnostic weight is -1.
Subjects in the initial investigation were participants in an open-label, multicenter, international Phase III study in which patients were randomized to be treated with either the standard-of-care 5-FU/LV chemotherapy (control arm) regimen alone or 5-FU/LV chemotherapy co-administered with SU5416 (treatment arm) administered twice weekly via intravenous infusion at a dose of 145 mg/m 2(for more detail see [ 13 14 ] ). Affymetrix expression profiling technology was applied to RNA from matched peripheral blood mononuclear cell (PBMC) sample pairs (before and after treatment) harvested from subjects, for assessment of changes in gene expression that might correlate with SU5416 administration.
Interestingly, inhibition of Rho-p160ROCK has recently been shown to give similar lymphocyte morphology as inhibition of Rho with C3 [ 50 ] . Another interesting candidate may be p120 PKN, as recent studies have established that PKN phosphorylates cytoskeletal intermediate filaments [ 47 ] and is directly linked to the cytoskeletal network through associations with α-actinin [ 48 ] . Also, PKN may be involved in relating cytoplasmic signals to the nucleus, for in response to stress, nuclear translocation of PKN occurs [ 49 ] . This is particularly important in light of previous work demonstrating that inactivation of Rho in peripheral blood T lymphocytes inhibits costimulatory signals up-regulating IL-2 production [ 25 ] . Future experiments will focus on determining the relationship of Rho GTPases and the regulation of T cell morphology [ 25 51 52 ] .
Loading...