Words similar to pcd

Example sentences for: pcd

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These compounds can activate some nuclear receptors including steroidogenic factor 1 [ 44 ] and LXR, which may be partially responsible for their biological activities [ 45 46 ] . Cholesterol oxides are inhibitors of HMG-CoA reductase, the key enzyme of cholesterol biosynthesis pathway [ 47 ] . The ability to bind to an intracellular receptor, oxysterol binding protein, may be responsible for their inhibition of cholesterol biosynthesis [ 48 49 ] . It should be noted that addition of cholesterol does not prevent cholesterol oxide induced cell death, which leads to the suggestion that inhibition of cholesterol synthesis is not the cause of cholesterol oxide induced PCD [ 50 51 ] . The critical events that result in cholesterol oxide induced cytotoxicity remain to be determined.
During growth factor deprivation induced PCD in neuronal PC12 cells, there is a sustained activation of the JNK and p38 pathways while the activities of ERK pathway is inhibited.
To facilitate the selection of PcrG variants that functioned to block Yops secretion (see below), the virulence plasmid, pCD1, of the lcrG Y. pestis strain KIM8-3002.
Fluorescent programmed cell death (PCD) assays
Given the suggestion that an up-regulation of c-jun is a cause of PCD [ 15 16 ] , a reduction in c-jun activation by PPAR agonists should attenuate 25-OH-cholesterol induced cytotoxicity.