Example sentences for: paralogs

How can you use “paralogs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In an attempt to isolate the effect of duplication per se on purifying selection, we analyzed paralogs and orthologs that appeared to encode proteins with similar functions, namely secreted and membrane proteins that were identified by signal peptide and transmembrane helix prediction.

  • On the other hand, origin as ancient paralogs is also a possibility.

  • One of the predictions of the conventional model of evolution of duplicated genes is the rapid loss of paralogs due to null mutations [ 2, 3, 5, 7].

  • Here we show that the same pattern of purifying selection is observed among bacterial and archaeal paralogs and demonstrate that amino-acid substitution rate is greater in paralogs than in orthologs with the same level of divergence at synonymous sites.

  • A comparison of the evolutionary distances between each of the paralogs and the ortholog used as an outgroup showed that, of a total of 101 analyzed pairs, only five evolve at significantly ( p < 0.05) different rate.


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