Example sentences for: paralogs

How can you use “paralogs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • When two paralogs of such a bifunctional gene are produced by duplication, each may be driven by positive selection to specialize in one of these functions, which it performs more efficiently than the ancestor gene, leading to the creation of two indispensable genes with distinct functions [ 11].

  • Each file includes annotated lists of clusters of recently duplicated paralogs (see text for the definitions) from the corresponding genome or, in the case of archaea and bacteria, from the set of all available complete genomes.

  • Multiple paralogs of both H-rev107 and NSE2 are seen in vertebrates, suggesting some functional diversification of these subgroups.

  • During this period, both genes might accumulate mutations that impair different functions of the ancestral gene, so that, after a certain point, none of the paralogs is capable of substituting for the ancestor [ 6, 10].

  • The results of the present analysis of recent duplications suggest a two-stage evolutionary model of gene duplication: in the first stage, immediately after duplication and during the early phase of their evolution, paralogs are retained and are subject to purifying selection because of the short-term advantage of protein dosage regulation; at a later stage in their evolution, gene duplications are likely to provide a long-term advantage by enabling the creation of new functions.


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