Example sentences for: paralogous

How can you use “paralogous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The conventional view, pioneered by Susumu Ohno, holds that a gene duplication produces two functionally redundant, paralogous genes and thereby frees one of them from selective constraints.

  • GenProtEC also contains imputed function assignments based on sequence similarity to orthologous or paralogous proteins, on gene (operon) location and on phenotypes of mutants [ 18].

  • This contrasts with observations of miRNAs in vertebrates, where the majority of known miRNAs are members of paralogous gene sets [ 31 ] . The most extreme examples of this disparity are let-7 and mir-29 , which are present in single copies in Drosophila , but are represented by thirteen and six distinct human homologs, respectively.

  • However, a principle of phylogenomics is that orthologous sequences (that diverged by speciation) are more likely to conserve protein function than paralogous sequences (that diverged by gene duplication).

  • In the archaeo-eukaryotic lineage, there is a duplication of the α-subunit, resulting in two paralogous subunits, RBP3 and RBP11.


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