Example sentences for: pai-

How can you use “pai-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To provide the evidence to support the conclusion obtained from enzyme assay, certain amount of wtPAI-1, E351R and E351A were incubated with equal amount of tPA at 37°C for 30 minutes before put on ice, at same time these PAI-1s were incubated in PBS at 37°C for 3 hours, respectively, before the PAI-1s were incubated with same amount of tPA at 37°C for 30 minutes, then the protein samples prepared at two time points were subjected to SDS-PAGE and western blot as described before.

  • tPA, tissue-type plasminogen activator; uPA, urokinase-type plasminogen activator; PAI-1, plasminogen activator inhibitor type 1; serpin, serine protease inhibitor; RCL, reactive center loop; Vn, vitronectin, SDS, sodium dodecylsulfate; PAGE, polyacrylamide gel electrophoresis.

  • [ 6 7 8 ] The essential function of PAI-1 in the fibrinolytic system has been confirmed by studies with transgenic animals.

  • More importantly, Glu351 of PAI-1 is a specificity determinant for uPA, thrombin and plasmin, but not for tPA.

  • [ 15 27 ] The specificity of the two mutants toward thrombin and plasmin implicates that Glu351 of PAI-1 is involved in its specificity toward thrombin and plasmin.


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