Example sentences for: pai-

How can you use “pai-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The P1 (Arg346) residue in the RCL of PAI-1 is an essential determinant for its target specificity and inhibitory activity.

  • 5 ug of Fibrosarcoma PAI-1, or wtPAI-1 was denatured by boiling for 5 min in a buffer consisted of 0.5% SDS, 50 mM β-mercaptoethanol and 50 mM Tris-HCl, pH 7.4.

  • [ 17 18 19 ] Furthermore, Glu350 (P4') of PAI-1 has been shown to mediate the interactions with tPA.

  • [ 26 ] Furthermore, the rapid inhibition of plasmin requires a non-covalent interaction between an amino-terminal site of plasmin and a carboxyl-terminal on anti-plasmin, and a second site outside the RCL of PAI-1 contributes to its specific interaction with proteases.

  • The high specific inhibitory activity of wt-PAI-1 could be due to the fact that it was secreted from insect High-5 cells cultured at 27°C, while the fibrosarcoma preparation of PAI-1 was obtained from the medium of fibrosarcoma cells cultured at 37°C [ 20 ] . Exposure to the higher temperature could accelerate the conversion of the inhibitor into its latent form.


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