Example sentences for: pai-

How can you use “pai-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 3A) just as fibrosarcoma PAI-1.

  • Plasminogen activator inhibitor-1 (PAI-1) and PTHrP are known target genes of TGFβ signalling.

  • We have previously demonstrated that TGFβ upregulates PTHrP and PAI-1 RNA levels in MDA-MB-231 cells [ 19 ] . TGFβ affected PTHrP expression primarily by increasing the level of the promoter P3-specific transcript [ 19 ] . Quantitative PCR analysis using primers allowing the detection of PTHrP P3 and PAI-1 transcripts indicated that incubation of MDA-MB-231 cells with SB-202190 and SB-203580 greatly inhibited TGFβ-induced increase in PTHrP and, to a lesser extent, PAI-1 mRNA levels (Fig.

  • For example, positively charged amino acids in the variable region of tPA, uPA and thrombin play dominant roles in the specific interaction with PAI-1.

  • PAI-1 inhibitory activity is expressed as the number of international units of PAs inhibited by PAI-1.


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