Example sentences for: pai-

How can you use “pai-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To the best of our knowledge, this is the first time that the specificity of PAI-1 toward uPA is partially mediated by the negatively charged residue located in the C-terminal of cleavage site in PAI-1.

  • To elucidate the mechanism through which such mutations affect the activity of PAI-1, we determined their effect on the functional stability of PAI-1 and on its ability to form an SDS stable complex with either tPA or uPA.

  • Complex formation of the fibrosarcoma PAI-1, wtPAI-1 or its mutants with single-chain tPA or uPA were performed as described earlier [ 20 ] . Samples of PAI-1s (5 U) were incubated in the absence or in the presence of a 2-fold excess of uPA or tPA in the activity assay buffer.

  • The inhibitory activity of each of the PAI-1s was assayed immediately.

  • More importantly, amount complexes formed by tPA and PAI-1s remained after incubation at 37°C (Fig.


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