Example sentences for: paf

How can you use “paf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • WE carried out quality control, procedural documentation, statistical modeling, and PAF calculations under the guidance of TJA.

  • Assuming a causal relationship between tap water consumption and the development of cryptosporidiosis in persons with AIDS, the PAF was 85%; that is, the proportion of cases in San Francisco AIDS patients attributable to tap water consumption could have been as high as 85%.

  • The 1.0 MDa complex contains yCCR4, yPOP2 (also referred to as yCAF1) and at least five yNOT1-5 proteins [ 5 6 7 ] . In this complex, yPOP2 independently binds to yCCR4 and yNOT1, and is absolutely required for yCCR4 to associate with the 1.0 MDa complex [ 6 7 ] . In the 1.9 MDa complex, yCCR4 binds to proteins such as yDBF2, a cell-cycle regulated protein kinase [ 2 ] , yCAF4 and yCAF16, and is essential for the interaction of both yCAF4 and yCAF16 with ySRB9, a component of the RNA polII holoenzyme [ 8 ] . yCCR4 was also reported to be associated with Paf1, Cdc73, and Hpr1 in a RNA polII complex distinct from the SRBP-containing holoenzyme [ 9 ] . Accordingly, yCCR4 contains, in its central region, a leucine-rich repeat (LRR) domain [ 10 ] which was demonstrated to be necessary for yCCR4 binding to the yPOP2 [ 5 11 ] , yDBF2 [ 2 ] , yCAF4 and yCAF16 [ 8 ] components of the CCR4-NOT complex.

  • This finding is significant given prior reports that oxidative stress on RPE is an important contributing factor of age-related macular degeneration [ 5 42 ] . An earlier report also indicated that PPARγ agonists could prevent laser photocoagulation induced choroidal neovascularization in rat eyes and monkey eyes, which suggests the possible application of these agents on the exudative form of age-related macular degeneration [ 43 ] . It is important to note that the other PPARγ agonists tested in this study (ciglitazone, azelaoyl PAF and LY171883) were ineffective in saving cells under the same experimental conditions.

  • He also is principal investigator in the PAF Acetylhydorolase study carried out by ICOS, Bothell, WA.


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