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Example sentences for: pai
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Likewise, Arabidopsis PAI2 and PAI3 genes that have been trans-methylated by the PAI1/PAI4 locus do not transfer their methylation status to naive singlet genes [ 12 ] . In fact, there are few well-documented cases for the non-allelic relay of trans-silencing ability [ 11 24 ] . Does this amount to an operational difference between allelic (paramutation) and non-allelic (trans-silencing) interactions, or does it simply reflect a lack of data?
It is informative to compare the epigenetic interactions of the 35S:GFP-COP1 transgenes with those of the PAI (trans)genes, the only other well-characterized system in Arabidopsis [ 12 ] . Both gene sets consist of relatively simple repeat structures and singlet loci, which reside in essentially single-copy environments of Arabidopsis ( [ 27 ] and unpublished observations).
The methylation status of the maize r1 genes and Arabidopsis PAI genes is altered upon paramutation [ 12 19 ] , while that of maize b1 is not [ 1 ] , except, in the non-conventional way, in the distal paramutation-control region of b1 [ 18 ] . Conversely, extensive exposure of a wild-type Arabidopsis SUPERMAN allele to a heavily methylated and transcriptionally silenced epiallele did not reveal any trans-silencing [ 20 ] .
In contrast, a trans-methylated singlet PAI2 gene did not trans-methylate a naive allelic PAI2 gene within three generations [ 12 ] . Additional experimentation may eventually provide an answer to the question of what controls the efficiency of such epigenetic interactions.
Midway along the Long Corridor at the foot of Longevity Hill is the Hall of Dispelling Clouds (Pai Yun Dian), where Cixi held her birthday parties.
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