Words similar to p-tef
Example sentences for: p-tef
How can you use “p-tef” in a sentence? Here are some example sentences to help you improve your vocabulary:
How central will the regulation of P-TEFb be to cellular growth, proliferation, and differentiation, and what roles will it play in normal development and disease states?
The final proof that P-TEFb is the cellular cofactor for Tat came from studies of HIV transcription in murine cells, where the introduction of the human CycT1 protein restores Tat function [12].
P-TEFb phosphorylates the carboxy-terminal domain of the RNA polymerase II complex [ 12], facilitating transcription elongation.
These are exciting findings and suggest a plethora of future experiments, including the genetic inactivation of subunits of P-TEFb and isoforms of HEXIM1 in the mouse.
Actinomycin D inhibits transcription initiation broadly by intercalating into DNA whereas DRB inhibits the transcription elongation factor P-TEFb [ 12].