Words similar to p-tef
Example sentences for: p-tef
How can you use “p-tef” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cdc37, like its higher eukaryotic homologs, promotes the physical integrity of multiple protein kinases, perhaps by virtue of a cotranslational role in protein folding [ 80 ] . Finally, Hsp90/Cdc37 has recently been shown in the stabilization/folding of Cdk9 as well as the assembly of an active Cdk9/cyclin T1 complex responsible for P-TEFb-mediated Tat transactivation [ 81 ] .
Recently, important aspects of the regulation of P-TEFb have been revealed (Figure 2).
A paper in this issue of PLoS Biology suggests that Tat and P-TEFb can also recruit TAF-independent transcription complexes to the HIV LTR [14] (Figure 1).
How central will the regulation of P-TEFb be to cellular growth, proliferation, and differentiation, and what roles will it play in normal development and disease states?
As to HIV, how can we use our knowledge of P-TEFb to slow down viral replication and/or to eliminate the state of proviral latency in the host?
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