Example sentences for: p-tef

How can you use “p-tef” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • How central will the regulation of P-TEFb be to cellular growth, proliferation, and differentiation, and what roles will it play in normal development and disease states?

  • The final proof that P-TEFb is the cellular cofactor for Tat came from studies of HIV transcription in murine cells, where the introduction of the human CycT1 protein restores Tat function [12].

  • P-TEFb phosphorylates the carboxy-terminal domain of the RNA polymerase II complex [ 12], facilitating transcription elongation.

  • These are exciting findings and suggest a plethora of future experiments, including the genetic inactivation of subunits of P-TEFb and isoforms of HEXIM1 in the mouse.

  • Actinomycin D inhibits transcription initiation broadly by intercalating into DNA whereas DRB inhibits the transcription elongation factor P-TEFb [ 12].


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