Example sentences for: p-tef

How can you use “p-tef” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • P-TEFb contains the cyclin-dependent kinase 9 (CDK9) and one of four possible C-type cyclins.

  • In this way, Tat can reassemble with P-TEFb on TAR.

  • Conversely, the inhibition of P-TEFb could explain the mode of action of some transcriptional repressors.

  • Cdc37, like its higher eukaryotic homologs, promotes the physical integrity of multiple protein kinases, perhaps by virtue of a cotranslational role in protein folding [ 80 ] . Finally, Hsp90/Cdc37 has recently been shown in the stabilization/folding of Cdk9 as well as the assembly of an active Cdk9/cyclin T1 complex responsible for P-TEFb-mediated Tat transactivation [ 81 ] .

  • Of interest, P-TEFb exists in two complexes in cells [22,23].


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