Example sentences for: p-tef

How can you use “p-tef” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, as P-TEFb is a coactivator of potent activators that mediate effects of enhancers and can itself activate transcription when placed on sites distal to promoter elements [15], it might mediate many more signaling events than those of heat shock, ultraviolet light, stress, and hypertrophy.

  • How central will the regulation of P-TEFb be to cellular growth, proliferation, and differentiation, and what roles will it play in normal development and disease states?

  • The larger measures approximately 500 kDa and contains the hexamethylene bisacetamide (HMBA)–induced protein 1 (HEXIM1) and 7SK small nuclear RNA (snRNA) in addition to P-TEFb [24,25].

  • This activation domain binds cyclin T1 (CycT1) from P-TEFb, whose partner is CDK9 [12].

  • P-TEFb phosphorylates the carboxy-terminal domain of the RNA polymerase II complex [ 12], facilitating transcription elongation.


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