Example sentences for: over-expression

How can you use “over-expression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Many of the cell lines showed modest levels of over-expression of the fusion proteins relative to levels of BLM found in a normal SV40-transformed cell line.

  • To test for overexpression of the mutant enzymes, E. coli BL21(DE3)pLysS cells were transformed with the mutated over-expression plasmids, and small scale growth cultures were used [ 68 ] . Large-scale (4 L) preparations of the L1 mutants were performed as described previously [ 36 ] . Protein purity was ascertained by SDS-PAGE.

  • The stable nucleolar localization of BLM is not due to over-expression but rather to a function encoded in the C-terminus of BLM.

  • The results of all the experiments did not confirm the over-expression of PAC-1 . Therefore, to obtain more information about the structure of the PAC-1 related genes in leukemic LGL, we screened an LGL leukemia cDNA library using a 1.2 kb PAC-1 cDNA fragment and identified similar genes which are different forms of PAC-1 (GenBank Accession #AF331843, the other sequence is not deposited).

  • Modulation of the expression of EGF and its receptor (EGF-R) in prostate cells by androgen [ 18 19 26 ] , and over-expression of EGF-R during the advanced stages of prostate cancer [ 34 ] , imply that EGF/EGF-R signaling events might be involved in neoplasia and perhaps progression of prostate cancer.


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