Words similar to over-expression
Example sentences for: over-expression
How can you use “over-expression” in a sentence? Here are some example sentences to help you improve your vocabulary:
The over-expression plasmid for L1, pUB5832, was digested with Nde I and Hind III, and the resulting ca. 900 bp piece was gel purified and ligated using T4 ligase into pUC19, which was also digested with Nde I and Hind III, to yield the cloning plasmid pL1PUC19.
Over-expression of homeodomain-interacting protein kinase 2 (HIPK2), which increases p53 protein expression and/or stability, leads to a downregulation of mdm2 protein, but not mRNA [ 29 ] . Consequently, the RU486-induced increase in mdm2 mRNA expression, coupled with a decrease in that of P53, may also act in tandem to suppress the liver apoptotic capacity (Fig 1B).
The results of all the experiments did not confirm the over-expression of PAC-1 . Therefore, to obtain more information about the structure of the PAC-1 related genes in leukemic LGL, we screened an LGL leukemia cDNA library using a 1.2 kb PAC-1 cDNA fragment and identified similar genes which are different forms of PAC-1 (GenBank Accession #AF331843, the other sequence is not deposited).
RP L4/L1 transcripts, which were not significantly affected by NGF, are selectively upregulated in PC12 cells prior to 5 aza cytosine-induced death and over-expression of this gene in COS-7 cells induces apoptosis [ 39 ] . Over-expression of L7, L13A, S29 have been also reported to induce apoptosis [ 40 41 ] . In the present study, NGF promoted little if any change in expression of these RP transcripts.
A partial cDNA clone homologous to AtCOP1 has been previously identified in mammals, containing all three conserved protein-protein interaction domains [ 20 ] . Remarkably, when expressed in plant cells, the mammalian COP1-reporter fusion protein exhibited a light-regulated nuclear localization pattern similar to AtCOP1 [ 20 ] . Although mammalian COP1 failed to rescue the Arabidopsis cop1 mutants, over-expression of the amino-terminal half of mammalian COP1 in Arabidopsis caused a dominant-negative phenotype, resembling the effect of over-expressing the corresponding fragment of AtCOP1 [ 20 21 ] .
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