Example sentences for: over-expression

How can you use “over-expression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In mouse models, over-expression of TGF-β 1 in the mammary gland protects against tumorigenesis [ 11], whereas local inactivation of the type II TGF-β receptor enhances tumorigenesis [ 32].

  • Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.

  • Thus, for non-N-myc transfected neuroblastoma cells and PC12 cells (± NGF) the contribution of total RP transcripts lies in a similar range and this parameter is greatly elevated in neuroblastoma cells by N-myc over-expression.

  • These two genes share approximately 80% similarity at the DNA level but have different enzymatic activities [ 13 14 ] . Using either one of the genes as a probe, both cDNA microarray and northern blot analysis indicated over-expression of both genes indiscriminately (Fig.

  • Using a cDNA fragment identical to the PAC-1 probe on the cDNA microarray, we performed a Northern blot analysis and confirmed the over-expression of two transcripts in leukemic LGL cells (Fig.


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