Example sentences for: over-expression

How can you use “over-expression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Previous studies from our laboratory have consistently demonstrated loss of the SpeB phenotype in S. pyogenes isolates injected in a skin air sac and recovered from the organs of lethally infected mice [ 10 16 ] . This selection was not associated with loss of β-hemolysis but was associated with over-expression of M and M-related proteins, which in turn are predictive of the invasive potential of the organism in a skin infection model [ 16 ] . Based on the phenotypic characteristics of the kidney-recovered variant (β-hemolytic positive, M and M-related protein positive and SpeB negative) we predicted that this variant would be as virulent or more virulent than the wild type organism in the mouse skin infection model.

  • In mouse models, over-expression of TGF-β 1 in the mammary gland protects against tumorigenesis [ 11], whereas local inactivation of the type II TGF-β receptor enhances tumorigenesis [ 32].

  • (1) The over-expression levels of mutants were analyzed with SDS-PAGE to ensure that the mutations did not result in changes in the over-expression levels of the enzymes.

  • Large-scale over-expression and purification of the Y228A and Y228F mutants showed that both mutants were isolatable at levels comparable to those of wild-type L1.

  • The significance of over-expression of the mitochondrial ATPase 6 gene in P. carinii -infected lung is unknown.


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