Example sentences for: over-expressed

How can you use “over-expressed” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • While identifying individual differentially expressed genes attracts most of the interest, a genome wide transcriptome map may not only provide a tool to identify candidate genes that are over-expressed or silenced in certain disease tissue, but may also help to understand the structure and organization of the genome.

  • The ΔN2 protein is relatively over-expressed under the induction conditions used, while the ΔN3 and ΔN4 proteins are expressed at near normal levels under the same induction conditions.

  • In this study, we used it to detect genes that are over-expressed in P. carinii -infected cells.

  • These data indicate that the over-expressed STAT3 observed in NRP-154 cells in the gene microarray was putatively active as a transcription factor, since the amount of phospho-STAT3 in NRP-154 cells was increased relative to NRP-152 cells.

  • Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are nuclear transcription factors that mediate the action of retinoids [ 11 12 ] . We have demonstrated that in the rat, castration resulted in an increase in mRNAs for RAR α and γ in the prostate; such effects were prevented by T replacement [ 13 ] . We also demonstrated that the levels of mRNAs for RAR α and γ in non-tumorigenic rat epithelial cells (NRP152) were down-regulated, whereas those in tumorigenic cells (NRP154) were unaffected or up-regulated following T treatment [ 14 ] . In addition, RAR α was over-expressed in tumorigenic NRP154 cells.

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