Words similar to over-expressing
Example sentences for: over-expressing
How can you use “over-expressing” in a sentence? Here are some example sentences to help you improve your vocabulary:
Since the SP-B gene is known to be expressed only in type II pneumocytes and Clara cells, the results suggest that these two types of cells are over-expressing the ATPase 6 gene in response to P. carinii infection.
These possibilities could be distinguished by transformation of plasmids from individual clones into the σ E-over-expressing strain and directly comparing of XylE activity in the presence and absence of σ E. Unfortunately, it appears that expression of XylE in M. smegmatis may be detrimental and may lead to plasmid instability and loss of the inserted DNA.
This result was reminiscent of an earlier study conducted by our laboratory using the mga mutant of isolate 64/14 [ 9 ] . In this case, although the mga mutant failed to express M or M-related proteins, however, it was capable of causing a lethal infection [ 9 ] . Detailed analysis of this system indicated that the mouse was capable of selecting an M protein over-expressing variant despite the presence of the mga mutation in an identical location [ 9 ] .
To develop the I-TRAP method for identifying M. tuberculosis promoters dependent on the expression of σ E, a strain of M. smegmatis over-expressing the M. tuberculosis σ E, a σ Emutant strain of M. smegmatis, and a M. tuberculosis promoter-trap library were created.
A partial cDNA clone homologous to AtCOP1 has been previously identified in mammals, containing all three conserved protein-protein interaction domains [ 20 ] . Remarkably, when expressed in plant cells, the mammalian COP1-reporter fusion protein exhibited a light-regulated nuclear localization pattern similar to AtCOP1 [ 20 ] . Although mammalian COP1 failed to rescue the Arabidopsis cop1 mutants, over-expression of the amino-terminal half of mammalian COP1 in Arabidopsis caused a dominant-negative phenotype, resembling the effect of over-expressing the corresponding fragment of AtCOP1 [ 20 21 ] .