Example sentences for: orphan

How can you use “orphan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The remaining two significantly regulated genes (for orphan nuclear hormone receptor BD73 and pepsinogen C) were initially identified as downregulated by greater than fourfold.

  • What if he goes nuts one day and slaps the hell out an orphan, or even better, Trent Lott?

  • Tie1 is an orphan receptor, whereas the ligands of Tie2 receptor have been identified as angiopoietin (Ang)-1 and Ang-2 [ 5 6 ] . Ang-1 has been shown to be responsible for recruiting and sustaining periendothelial support cells [ 7 ] . It has been reported that Ang-2 disrupts blood vessel formation in the developing embryo by antagonizing Ang-1-induced autophosphorylation of Tie2 [ 6 ] . Transgenic mouse models of Tie2/Ang-1 result in embryonic lethality due to absence of remodeling and sprouting of blood vessels [ 7 8 ] . The physiologic roles of the Tie2 receptor and its ligands are limited to angiogenic processes that occur subsequently to the earlier vasculogenic and angiogenic actions of vascular endothelial growth factor (VEGF) and its receptors [ 7 ] . VEGF and the Tie family orchestrate optimal blood vessel formation [ 9 10 ] .

  • “Chutzpa is that quality enshrined in a man, who, having killed his mother and father, throws himself on the mercy of the court because he is an orphan.

  • The owner, a member of one of Cuba’s most important families, rescued orphan girls and took them into his home — his obra pía (work of piety) that lends its name to both the house and its street.


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