Words similar to orphan
Example sentences for: orphan
How can you use “orphan” in a sentence? Here are some example sentences to help you improve your vocabulary:
If this interpretation is correct, our results confirm those of Schmid and co-workers [ 34, 59] who have shown that a large fraction of randomly sampled coding sequences and orphan genes are rapidly evolving in the genus Drosophila . Our results are also consistent with those of Ashburner et al . [ 60] who show that genes with known mutant phenotypes in D. melanogaster are more likely to have a conserved homolog in GenBank relative to predicted genes with no known phenotype.
Starr pressured Kathleen Willey's friend Julie Hiatt Steele by questioning the legality of her adoption of a Romanian orphan.
The 26S proteasome is responsible for the bulk turnover of cytoplasmic and nuclear proteins in eukaryotic cells and also plays a key role in the regulation of cell cycle, signal transduction, transcription as well as antigen presentation [ 17 18 19 20 21 ] . Most of the known proteasomal substrates are marked and targeted to proteasome by ubiquitination [ 17 19 20 ] . Ubiquitination, however, is not an obligatory step for substrate targeting to proteasome [ 17 18 20 ] . The degradation of the ornithine decarboxylase (ODC), the rate-limiting enzyme for polyamine synthesis, involves a protein named antizyme (Az), which binds and targets ODC to 26S proteasome for degradation [ 18 ] . However, ODC has remained an "orphan" in Az-dependent proteasomal degradation.
18: Rebel Without a Lollipop --Confused, rebellious teen (James Dean) receives life lesson from poor orphan girl (Shirley Temple); the teen's later, tragic death inspires girl to life in foreign service.
This approach might help to inform the development of business models for the production and distribution of orphan biologics for other neglected diseases.
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