Example sentences for: orphan

How can you use “orphan” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The 26S proteasome is responsible for the bulk turnover of cytoplasmic and nuclear proteins in eukaryotic cells and also plays a key role in the regulation of cell cycle, signal transduction, transcription as well as antigen presentation [ 17 18 19 20 21 ] . Most of the known proteasomal substrates are marked and targeted to proteasome by ubiquitination [ 17 19 20 ] . Ubiquitination, however, is not an obligatory step for substrate targeting to proteasome [ 17 18 20 ] . The degradation of the ornithine decarboxylase (ODC), the rate-limiting enzyme for polyamine synthesis, involves a protein named antizyme (Az), which binds and targets ODC to 26S proteasome for degradation [ 18 ] . However, ODC has remained an "orphan" in Az-dependent proteasomal degradation.

  • Starr pressured Kathleen Willey's friend Julie Hiatt Steele by questioning the legality of her adoption of a Romanian orphan.

  • What if he goes nuts one day and slaps the hell out an orphan, or even better, Trent Lott?

  • This gene is found on the same contig as D1S490 (NT_004817) and is an orphan receptor within the steroid hormone receptor superfamily.

  • Moreover, Alimi et al . [ 21 ] have shown that at least some of the orphan genes in E. coli are indeed transcribed.


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