Words similar to orphan
Example sentences for: orphan
How can you use “orphan” in a sentence? Here are some example sentences to help you improve your vocabulary:
If this interpretation is correct, our results confirm those of Schmid and co-workers [ 34, 59] who have shown that a large fraction of randomly sampled coding sequences and orphan genes are rapidly evolving in the genus Drosophila . Our results are also consistent with those of Ashburner et al . [ 60] who show that genes with known mutant phenotypes in D. melanogaster are more likely to have a conserved homolog in GenBank relative to predicted genes with no known phenotype.
Michael Caine's turn as the benign head of the orphanage (a doctor addicted to ether) is excellent, but Tobey Maguire, playing the orphan Caine takes under his wing and grooms to be his successor, is too deadpan for most critics.
Another says an orphan was killed, salted, and eaten.
Tie1 is an orphan receptor, whereas the ligands of Tie2 receptor have been identified as angiopoietin (Ang)-1 and Ang-2 [ 5 6 ] . Ang-1 has been shown to be responsible for recruiting and sustaining periendothelial support cells [ 7 ] . It has been reported that Ang-2 disrupts blood vessel formation in the developing embryo by antagonizing Ang-1-induced autophosphorylation of Tie2 [ 6 ] . Transgenic mouse models of Tie2/Ang-1 result in embryonic lethality due to absence of remodeling and sprouting of blood vessels [ 7 8 ] . The physiologic roles of the Tie2 receptor and its ligands are limited to angiogenic processes that occur subsequently to the earlier vasculogenic and angiogenic actions of vascular endothelial growth factor (VEGF) and its receptors [ 7 ] . VEGF and the Tie family orchestrate optimal blood vessel formation [ 9 10 ] .
The remaining two significantly regulated genes (for orphan nuclear hormone receptor BD73 and pepsinogen C) were initially identified as downregulated by greater than fourfold.
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