Example sentences for: opioids

How can you use “opioids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • While a trial of opioids may be beneficial in the unconscious patient who is difficult to assess, physicians must remember that opioids may accumulate and add to delirium when renal clearance is poor [ 91 92 ] . If the trial of increased opioids does not relieve the agitation, or makes the delirium worse by increasing agitation or precipitating myoclonic jerks or seizures (rare), then pursue alternate therapies directed at suppressing the symptoms associated with delirium.

  • Many physicians misperceive that respiratory depression is a significant risk when prescribing opioids for pain.

  • It has been postulated that activation of these kinases allows GPCR agonists to modulate such diverse molecular events as cell proliferation, differentiation, and survival [ 1 ] . To date, all three cloned opioid receptor types (μ,δ, κ) and the closely related nociceptin receptor have demonstrated the ability to signal through their heterotrimeric G proteins (G i or G o ) to at least one type of MAPK [ 2 3 4 ] . Among the members of this family that are activated by opioids, are the two extracellular signal-regulated protein kinases (p44 MAPK(ERK 1) and p42 MAPK(ERK 2)) [ 5 ] and the p38 protein kinase [ 3 ] . However, the precise mechanism by which OR stimulation produces an increase in MAPK activity is still unknown and under investigation.

  • Benzodiazepine medications may be combined safely with opioids [ 53 ] .

  • Constipation should be expected during opioid treatment and prophylactic measures always be initiated from the outset as the condition is easier to prevent than treat [ 68 ] . Opioids cause constipation, but they are not the only medication to do so.


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