Example sentences for: opioids

How can you use “opioids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Sedation in the terminal or final stages of life can be defined as the use of sedative drugs (usually benzodiazepines with or without complementary opioids given by the intravenous or by the subcutaneous route) to reduce the level of consciousness sufficiently deep to provide comfort for the patient until death occurs.

  • Constipation should be expected during opioid treatment and prophylactic measures always be initiated from the outset as the condition is easier to prevent than treat [ 68 ] . Opioids cause constipation, but they are not the only medication to do so.

  • In the presence of the EGFR, ligand activation of LPA and ET-1 receptors did not increase EGFR phosphorylation even though both the LPA and ET-1 receptors stimulated ERK activity by 10-fold over basal [ 27 ] . Specifically, key protein intermediates may be physically associated with endogenous RTKs in HEK-293 cells, and therefore, down-regulation of the EGFR may negatively affect ERK phosphorylation by opioids.

  • However, they found evidence for analgesic efficacy in established PHN for orally administered therapies, such as tricyclic antidepressants, some opioids, gabapentin, tramadol, and pregabalin.

  • When initiating or titrating analgesics, it is not necessary to traverse each step of the model sequentially; a patient with severe pain (7-10/10 on a numerical or visual analogue scale - NAS or VAS) may need to have step 3 opioids from the outset.


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