Words similar to opioids
Example sentences for: opioids
How can you use “opioids” in a sentence? Here are some example sentences to help you improve your vocabulary:
All of these opioids except fentanyl follow first-order kinetics.
Step 2 and 3 analgesics include the pure agonist opioids, eg, codeine, fentanyl, hydrocodone, hydromorphone, morphine, and oxycodone.
Our data clearly show that nalbuphine is a potent agonist at the μ opioid receptor with an efficacy similar to that of morphine, thus agreeing with in vivo data showing that morphine and nalbuphine are equally potent as analgesics [ 33 ] . However, other reports have described nalbuphine as a "mixed agonist/antagonist" with agonism at κ opioid receptors and antagonism at μ opioid receptors based on in vivo data [ 11 33 ] . This categorization is likely due to the fact that nalbuphine has been shown to reduce the ventilatory depressant effect of other opioids, while adding to their analgesic effect [ 33 ] . Nalbuphine is also used clinically to reduce the opioid-mediated side effects such as itching, without completely reversing the analgesic effects of the full agonists [ 34 35 36 ] . According to our data, although nalbuphine is clearly a potent agonist at μ receptors, its levels of agonism is significantly lower than the very efficacious drug fentanyl and the endogenous ligand β-endorphin.
Many physicians misperceive that respiratory depression is a significant risk when prescribing opioids for pain.
Sedation in the terminal or final stages of life can be defined as the use of sedative drugs (usually benzodiazepines with or without complementary opioids given by the intravenous or by the subcutaneous route) to reduce the level of consciousness sufficiently deep to provide comfort for the patient until death occurs.
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