Words similar to opioid
Example sentences for: opioid
How can you use “opioid” in a sentence? Here are some example sentences to help you improve your vocabulary:
The results describe the activity of a set of ligands not previously characterized at δ opioid receptors.
A single clone of transfected HEK cells stably expressing approximately 3 pmoles of μ opioid receptors per mg of protein, as measured by [ 3H]-DAMGO binding, was propagated and used as a model for characterization of the binding profiles of a set of opioid ligands at μ opioid receptors.
(3) These in vitro data can be utilized to define the physiochemical features of the ligands defining agonism and antagonism at δ opioid receptors, leading to design and discovery of novel opioid analgesics.
Thus the present study was designed, (1) to describe the activation profiles of a set of opioid ligands not previously defined at an isolated cell system expressing only δ opioid receptors, and (2) to compare the relative efficacies and potencies of these ligands to the strongest ligand in the set, metazocine, to the common opioid analgesic, morphine and to the endogenous δ opioid ligand, met-enkephalin.
The maximum effect of BW373U86 has been reported to be 70 ± 9% with IC 50 of 0.9 nM [ 21 ] . Some ligands that exhibited very low potencies in this study, such as fentanyl or metazocine, were amongst the most efficacious ligands tested suggesting that these ligands are capable of maximally activating δ opioid receptors.
Loading...