Example sentences for: opioid

How can you use “opioid” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Such information, combined with the knowledge on the physiochemical characteristics of the agonists and antagonists at each receptor, will lead to the design of novel opioid analgesics with minimal side effects.

  • Still, other reports, have suggested that opioid ligands with agonistic effect at μ opioid receptors and antagonistic effect at δ opioid receptors are potentially useful analgesics [ 3 17 18 ] . These latter results advocate that the key to designing opioid ligands with optimal analgesia and minimal side effects may be in the design of ligands that act on more than one receptor type, but activate each receptor differently.

  • Methadone, although the least expensive oral opioid, has a long and variable half-life (days).

  • For example, similar levels of expression have been measured for neuronal cells in culture (SH-SY5Y cells) [ 19 ] or primary cultures of dorsal root ganglion sensory neurons [ 20 ] . Thus, the level of μ receptor expression in the cell line used in this study is comparable to that of cells expressing the μ opioid receptors in various regions of the nervous system.

  • Stably transfected HEK cells were developed as described previously [ 33 ] . HEK 293 cells were transfected with the cDNA for mouse δ opioid receptor in the pCI-neo ®vector.


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