Words similar to ns-derived
Example sentences for: ns-derived
How can you use “ns-derived” in a sentence? Here are some example sentences to help you improve your vocabulary:
To investigate whether RA could stimulate development of NS-derived cells toward an IPC fate, we measured expression of Pdx1, Cdx1, and FoxA3, transcription factors that regulate gastrointestinal organ development [29,30].
We detected expression of the Hedgehog receptors Patched (Ptc) and Smoothened (Smo) at all stages (Figure 3B), consistent with the possibility that NS-derived cells are competent for Hh signaling.
After 2 wk at stage 2, NS-derived cells remained in clusters (see Figure 1A), but Nestin and Ki67 were expressed in fewer than 35% of cells (see Figure 2), indicating possible differentiation of cells toward lineage-restricted fates.
Moreover, stage 2 NS-derived cells expressed RA receptors including RAR-α and RAR-γ (see Figure 1C), indicating competence for RA signals.
At 300 nM, a dose used to induce neuronal development in ES cell cultures [21], Shh produced a significant increase in neurite outgrowth in NS-derived cells (Figure 3D and 3E; see Methods), and resulted in increased Ptc expression (Figure 3F).
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