Words similar to nsaids
Example sentences for: nsaids
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On the other hand, many synthetic compounds such as the non-steroid anti-inflammatory drugs (NSAIDs) are PPARα and PPARγ agonists [ 27 ] . Since these are agents used clinically for other purposes, it is important to determine whether interaction of these agents with PPARs could modulate atherogenesis in a positive or negative manner.
Although there is a growing body of epidemiological evidence on the role of aspirin and other NSAIDs in the chemoprevention of lung cancer (Table 1.; [ 14 17 18 19 20 21 22 23 ] ), about half of these studies published to date were not specifically designed to investigate this association [ 17 18 19 21 ] . In a randomized trial aimed at examining the effect of aspirin in the prevention of cardiovascular disease in male physicians, Peto et al [ 17 ] first noted lower lung cancer mortality rates in the aspirin intervention group compared to the placebo group.
Though this lesion is not specific for A-GVHD, it is a cardinal feature as demonstrated by experimental production of intestinal A-GVHD in the Rhesus monkey [ 14 25 ] . It is a valuable diagnostic feature in the absence of infections especially CMV [ 2 4 7 9 12 16 17 ] . Other critical differential diagnoses include effects of radiation-chemotherapy [ 12 13 ] and effects of other drugs such as NSAIDs [ 7 ] .
Various studies have reported increased levels of prostaglandins and COX-2 expression in colorectal adenomas and adenocarcinomas obtained both from animals [ 40 41 ] and humans [ 42 43 44 ] . These findings have lead to the implication that COX-2 plays an important role in intestinal neoplasia and that the anti-neoplastic effects of NSAIDs are attributable to their ability to inhibit COX-2.
Non-steroidal anti-inflammatory agents (NSAIDs), such as acetyl salicylic acid and indometasin, have been used in the treatment of sepsis and septic shock, and an improvement in survival has been noted.