Words similar to nrs

Example sentences for: nrs

How can you use “nrs” in a sentence? Here are some example sentences to help you improve your vocabulary:

The nuclear receptor (NR) family comprises 48 structurally related transcription factors, many of which require their cognate ligand for activity [ 1 2 3 ] . The NRs regulate transcription by binding to response elements in the promoters of target genes and acting as scaffolds for the assembly of large coactivator and corepressor complexes [ 4 ] . NR coactivators include the p160s (including GRIP1/TIF-2, SRC-1 and AIB1/ACTR/pCIP).
NRs consist of three domains, the N-terminal domain (which contains a context-specific activation function AF-1), the central DNA binding domain (DBD) and the C-terminal ligand binding domain (LBD), which contains a hormone-dependent activation function, AF-2.
Unliganded NRs usually bind ID motifs (consensus L/IXXIIXXXL) in the N-CoR C-terminus.
We do not understand why, but in our hands, transfected N-CoR also fails to affect TR or ERα activity (data not shown), despite the fact that it clearly interacts with both NRs.
JDB has proprietary interests in, and serves as consultant and deputy director to Karo Bio AB, a Swedish company that develops pharmaceuticals that target NRs.