Words similar to non-conserved

Example sentences for: non-conserved

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One is the cluster of basic residues KKKKRR (residues 768-773), located in a relatively non-conserved region of the AAA domain between AAA3 and AAA4.
Variations at residues alpha4 Thr183 and beta2 Ala135 generate different shapes of the binding pocket (Figure 4- Top), but preserve the electrostatic potential of the system: all non-conserved residues at position 183 are hydrophobic, and hydroxyl of Thr154 and Ser154 are superimposed, pointing away from the ligand, towards the carboxylate of Asp122.
Alignment of this sequence (amino acids 39 to 74) with the central conserved residues of motif I: A--GWEK---E---LK--L------------R--H-D (-- indicating non-conserved residues) shows a good match of identical and conserved amino acid residues: A--GFEK---D---LK--I---------R--H-E.
We eliminated those that contained more than four additional non-conserved positions in the non-miRNA-encoding arm compared to within the loop (Figure 2a, class 6), leaving behind class 3 candidates as potential miRNAs.
CASP1 was an eye-opener in terms of understanding the difficulty of making accurate predictions on approximate templates in comparative modelling [ 14 ] . The main problems in creating a good comparative or fold recognition model were related to alignment between the template and target sequences, and building of non-conserved variable regions (side chains, and main chain loops).