Words similar to nmj

Example sentences for: nmj

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We also investigated the distribution of gravin at the NMJ because this AKAP is an autoantigen for myasthenia gravis, a degenerative disease of the NMJ.
As shown in figure 4, RIIβ is found in the postsynaptic region of the NMJ and did not precisely overlap with the α-bungarotoxin label but instead encompassed a broader area of this region.
The labeling pattern of D-AKAP2 is diffuse in the NMJ, yet localized to the actin region in muscle.
However, a recent study showing the colocalization of D-AKAP1 with RI at the NMJ supports the prediction that localization of the R subunit there requires interaction with an AKAP [ 17 ] . RII has been shown to be associated with mAKAP in heart and skeletal muscle [ 20 21 ] ; however, little is known regarding the expression patterns of RII and AKAPs in the perijunctional regions.
Our interest in PKA and PKC activity in the NMJ derives from: (1) a report that RIα not only is enriched there, but also appears to be tethered to the postsynaptic membrane [ 19 ] , (2) the rich literature describing selective PKC isoform activity and functional compartmentalization in the NMJ and skeletal muscle, (3) our discoveries that D-AKAP1 and D-AKAP2 bind to and appear to colocalize with RIα, and often mitochondria [ 15 16 28 ] ; and (4) our finding that gravin binds to both PKA and PKC [ 13 ] .